Heterocyclic systems containing bridgehead nitrogen atom: Synthesis and biological activities of some substituted s-triazolo[3,4-b][1,3,4]thiadiazoles

被引：0

作者：

Gupta, R ^{[1
]}

Paul, S

Gupta, AK

Kachroo, PL

Bani, S

机构：

[1] Univ Jammu, Dept Chem, Jammu 180006, India

[2] Reg Res Lab, Dept Pharmacol, Jammu 180001, India

来源：

INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 1998年 / 37卷 / 05期

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D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Various 3-alky/aryl-6-(2-chloro-2-substituted-phenyl ethenyl)5, 6-dihydro-s-triazolo [3,4-b][1,3,4]-thiadiazoles 3 have been synthesised by the condensation of 3-substituted-4-amino-5-mercapto-1,2,4-triazoles with various substituted beta-chlorocinnamaldehydes 2 in benzene containing a catalytic quantity of p-TsOH using Dean-Stark apparatus. Structures of thiadiazoles 3 have been established on the basis of analytical and spectral data. The thiadiazoles 3 have been assessed for antiinflammatory, antibacterial and antifungal activities.

引用

页码：498 / 501

页数：4

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