A formal total synthesis of (-)-dysiherbaine

被引：28
|
作者：
Kang, SH [1 ]
Lee, YM [1 ]
机构：
[1] Korea Adv Inst Sci & Technol, Sch Mol Sci, Ctr Mol Design & Synth, Dept Chem, Taejon 305701, South Korea
来源：
SYNLETT | 2003年 / 07期
关键词：
glutamate receptors; (-)-dysiherbaine; hexahydrofuropyran; iodocyclization; mercuriocyclization;
D O I：
10.1055/s-2003-39318
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A key intermediate hexahydrofuropyran 2 to (-)-dysiherbaine 1 has been synthesized concisely via intramolecular oxymercuration and iodocyclization to install the asymmetric centers at the ring junction and the amino group in the tetrahydropyran stereoselectively.
引用
收藏
页码：993 / 994
页数：2
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