Genistein appears to prevent early postmenopausal bone loss as effectively as hormone replacement therapy

被引：50
|
作者：
Cotter, A [1 ]
Cashman, KD
机构：
[1] Natl Univ Ireland Univ Coll Cork, Dept Nutr & Food Sci, Cork, Ireland
[2] Natl Univ Ireland Univ Coll Cork, Dept Med, Cork, Ireland
来源：
NUTRITION REVIEWS | 2003年 / 61卷 / 10期
关键词：
genistein; phytoestrogens; postmenopausal bone loss; HRT;
D O I：
10.1301/nr.2003.oct.346-351
中图分类号：
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号：
100403 ;
摘要：
Recent data from a randomized, double-blind, placebo-controlled, yearlong clinical trial suggest that supplementation with the dietary phytoestrogen genistein (54 mg/day) may be as effective as hormone replacement therapy in attenuating menopause-related bone loss without causing the associated side effects. These findings may have implications for the development of diet-based strategies aimed at osteoporosis prevention.
引用
收藏
页码：346 / 351
页数：6
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