Synthesis and bioactivity of some new 3-(pyrazin-2′-yl)-6-aryl-5-pyrazinoyl-(6H)-1,2,4-triazolo (3,4-b) (1,3,4)-thiadiazolidines

被引：0

作者：

Gupta, VRM

Raviprakash, P

Varnekar, RB

Srinivasulu, N

Udupi, RH ^{[1
]}

机构：

[1] NET Coll Pharm, Dept Pharmaceut Chem, Raichur 584103, India

[2] VL Coll Pharm, Dept Pharmaceut Chem, Raichur 584101, India

来源：

INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY | 2005年 / 14卷 / 04期

关键词：

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Condensation of 3-(pyrazin-2'-yl)-4-(N-pyrazin-2"-yl carboxamido)-5-mercapto 1,2,4-triazole (3) with aromatic carboxaldehydes furnished in one step the cyclic products 3(pyrazin-2'-yl)-6-aryl/substituted aryl-5-pyrazinoyl-(6H)-1,2,4-triazolo (3,4-b) (1,3,4) thiadiazolidines (4a(1)-a(14)). The antibacterial, antifungal, antiinflammatory and analgesic activities of some of the compounds have been evaluated.

引用

页码：335 / 338

页数：4

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