LONG-TERM IMMUNITY AFTER TWO DOSES OF INACTIVATED HEPATITIS A VACCINE, IN ARGENTINEAN CHILDREN

被引：20
|
作者：
Lopez, Eduardo L. [1 ]
Contrini, Maria M. [1 ]
Mistchenko, Alicia [2 ]
Debbag, Roberto [3 ]
机构：
[1] Hosp Ninos Dr Ricardo Gutierrez, Program Infect Dis, Buenos Aires, DF, Argentina
[2] Hosp Ninos Dr Ricardo Gutierrez, Virol Lab, Buenos Aires, DF, Argentina
[3] Sanofi Pasteur, Buenos Aires, DF, Argentina
来源：
PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2010年 / 29卷 / 06期
关键词：
hepatitis A; immunization; pediatric; Argentina; FOLLOW-UP; IMMUNOGENICITY; IMMUNIZATION; SAFETY; ASSAYS;
D O I：
10.1097/INF.0b013e3181d57a85
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
We examined long-term anti-hepatitis A virus antibody persistence in Argentinean children 10 years after the initial study in which they received 2 doses of inactivated hepatitis A vaccine (Avaxim 80U). Of the 111 children, 48 from the initial trial were enrolled. Of 48, 47 (97.9%) participants had serum anti-hepatitis A virus antibody titers >= 20 mIU/mL, with the geometric mean concentration of 390.91 (+/-370.14) mIU/mL; (95% confidence interval, 282.2-499.5 mIU/mL), range, 36 to 1860.
引用
收藏
页码：568 / 570
页数：3
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