LONG-TERM IMMUNITY AFTER TWO DOSES OF INACTIVATED HEPATITIS A VACCINE, IN ARGENTINEAN CHILDREN

被引：20

作者：

Lopez, Eduardo L. ^{[1
]}

Contrini, Maria M. ^{[1
]}

Mistchenko, Alicia ^{[2
]}

Debbag, Roberto ^{[3
]}

机构：

[1] Hosp Ninos Dr Ricardo Gutierrez, Program Infect Dis, Buenos Aires, DF, Argentina

[2] Hosp Ninos Dr Ricardo Gutierrez, Virol Lab, Buenos Aires, DF, Argentina

[3] Sanofi Pasteur, Buenos Aires, DF, Argentina

来源：

PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2010年 / 29卷 / 06期

关键词：

hepatitis A; immunization; pediatric; Argentina; FOLLOW-UP; IMMUNOGENICITY; IMMUNIZATION; SAFETY; ASSAYS;

D O I：

10.1097/INF.0b013e3181d57a85

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We examined long-term anti-hepatitis A virus antibody persistence in Argentinean children 10 years after the initial study in which they received 2 doses of inactivated hepatitis A vaccine (Avaxim 80U). Of the 111 children, 48 from the initial trial were enrolled. Of 48, 47 (97.9%) participants had serum anti-hepatitis A virus antibody titers >= 20 mIU/mL, with the geometric mean concentration of 390.91 (+/-370.14) mIU/mL; (95% confidence interval, 282.2-499.5 mIU/mL), range, 36 to 1860.

引用

页码：568 / 570

页数：3

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