Extra- and intracellular antimycobacterial activity of Arbutus unedo L.

被引：8
|
作者：
El Ouarti, Asmae [1 ]
Haouat, Amina Cherif [1 ]
Sqalli, Hakima [1 ]
Haggoud, Abdellatif [1 ]
Ennabili, Abdeslam [2 ]
Ibnsouda, Saad [1 ]
Iachgar, Mohamed [3 ]
Iraqui, Mohammed [1 ]
机构：
[1] Univ Sidi Mohammed Ben Abdellah, Fac Sci & Tech Fes, Lab Biotechnol Microbienne, Fes 30000, Morocco
[2] Univ Sidi Mohammed Ben Abdellah, Inst Natl Plantes Med & Aromat, Taounate Principale 34015, Morocco
[3] Fac Sci Dhar EL Mehrez, Fes 30003, Morocco
来源：
AFRICAN JOURNAL OF MICROBIOLOGY RESEARCH | 2012年 / 6卷 / 06期
关键词：
Antimycobacterial activity; Arbutus unedo L; rat peritoneal macrophages; IN-VITRO ACTIVITY; MYCOBACTERIUM-TUBERCULOSIS; MEDICINAL-PLANTS; NATURAL-PRODUCTS; PATHOGENIC MYCOBACTERIUM; LEAF EXTRACTS; MACROPHAGES; RESISTANT; SMEGMATIS; MURINE;
D O I：
10.5897/AJMR11.1540
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
This study aims to evaluate extra- and intracellullar antimycobacterial activity of Arbutus unedo L. leaves-extracts. We tested the aqueous and ethanol extracts of Arbutus leaves effect against three mycobacteria growth, and showed that aqueous extract and the part I of ethanol extract have a remarkable extracellular antimycobacterial activity. The MIC (Minimum inhibitory concentration) of the part I of ethanol extract is 5.59 +/- 0.69 mg/ml for Mycobacterium aurum A + and 6.02 +/- 0.76 mg/ml for Mycobacterium smegmatis MC2 and Mycobacterium bovis PPI. The part I of arbutus ethanol-extract, used at 6.02 +/- 0.76 mg/ml, has a bactericidal effect on M. smegmatis MC2 located within the rat peritoneal macrophages.
引用
收藏
页码：1283 / 1290
页数：8
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