Extra- and intracellular antimycobacterial activity of Arbutus unedo L.

被引：8

作者：

El Ouarti, Asmae ^{[1
]}

Haouat, Amina Cherif ^{[1
]}

Sqalli, Hakima ^{[1
]}

Haggoud, Abdellatif ^{[1
]}

Ennabili, Abdeslam ^{[2
]}

Ibnsouda, Saad ^{[1
]}

Iachgar, Mohamed ^{[3
]}

Iraqui, Mohammed ^{[1
]}

机构：

[1] Univ Sidi Mohammed Ben Abdellah, Fac Sci & Tech Fes, Lab Biotechnol Microbienne, Fes 30000, Morocco

[2] Univ Sidi Mohammed Ben Abdellah, Inst Natl Plantes Med & Aromat, Taounate Principale 34015, Morocco

[3] Fac Sci Dhar EL Mehrez, Fes 30003, Morocco

来源：

AFRICAN JOURNAL OF MICROBIOLOGY RESEARCH | 2012年 / 6卷 / 06期

关键词：

Antimycobacterial activity; Arbutus unedo L; rat peritoneal macrophages; IN-VITRO ACTIVITY; MYCOBACTERIUM-TUBERCULOSIS; MEDICINAL-PLANTS; NATURAL-PRODUCTS; PATHOGENIC MYCOBACTERIUM; LEAF EXTRACTS; MACROPHAGES; RESISTANT; SMEGMATIS; MURINE;

D O I：

10.5897/AJMR11.1540

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

This study aims to evaluate extra- and intracellullar antimycobacterial activity of Arbutus unedo L. leaves-extracts. We tested the aqueous and ethanol extracts of Arbutus leaves effect against three mycobacteria growth, and showed that aqueous extract and the part I of ethanol extract have a remarkable extracellular antimycobacterial activity. The MIC (Minimum inhibitory concentration) of the part I of ethanol extract is 5.59 +/- 0.69 mg/ml for Mycobacterium aurum A + and 6.02 +/- 0.76 mg/ml for Mycobacterium smegmatis MC2 and Mycobacterium bovis PPI. The part I of arbutus ethanol-extract, used at 6.02 +/- 0.76 mg/ml, has a bactericidal effect on M. smegmatis MC2 located within the rat peritoneal macrophages.

引用

页码：1283 / 1290

页数：8

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