This note discusses a minor mathematical error and a problematic mathematical assumption in Luria and Delbruck's (1943) classic article on fluctuation analysis. In addition to suggesting remedial measures, the note provides information on the latest development of techniques for estimating mutation rates using data from fluctuation experiments.
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Univ Western Cape, S African Natl Bioinformat Inst, ZA-7535 Bellville, South AfricaUniv Western Cape, S African Natl Bioinformat Inst, ZA-7535 Bellville, South Africa
Swart, EC
Hide, WA
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Univ Western Cape, S African Natl Bioinformat Inst, ZA-7535 Bellville, South AfricaUniv Western Cape, S African Natl Bioinformat Inst, ZA-7535 Bellville, South Africa
Hide, WA
Seoighe, C
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Univ Western Cape, S African Natl Bioinformat Inst, ZA-7535 Bellville, South AfricaUniv Western Cape, S African Natl Bioinformat Inst, ZA-7535 Bellville, South Africa