Ischemic stroke after recombinant factor VIIa treatment in acquired hemophilia A patient

被引：4

作者：

Katgi, Abdullah ^{[1
]}

Ataca, Pinar ^{[2
]}

Kahraman, Selda ^{[1
]}

Piskin, Ozden ^{[1
]}

Ozcan, Mehmet A. ^{[1
]}

Demirkan, Fatih ^{[1
]}

Ozsan, Guner H. ^{[1
]}

Undar, Bulent ^{[1
]}

机构：

[1] Dokuz Eylul Univ, Dept Hematol, TR-35470 Izmir, Turkey

[2] Dokuz Eylul Univ, Dept Internal Med, TR-35470 Izmir, Turkey

来源：

BLOOD COAGULATION & FIBRINOLYSIS | 2012年 / 23卷 / 01期

关键词：

acquired hemophilia; recombinant factor VIIa; thromboembolic attack; INHIBITORS; METAANALYSIS; THERAPY;

D O I：

10.1097/MBC.0b013e32834b8267

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Acquired hemophilia is a rare, life-threatening coagulopathy in adults caused by the development of autoantibodies against factor VIII. Bypass agents such as recombinant factor VIIa (rFVIIa) are usually preferred for bleeding control; however, thromboembolic complications may occur. We report here a case that presented with extensive cutaneous and mucosal bleedings due to factor VIII inhibitors and was treated successfully with rFVIIa and steroid therapy, but was complicated with a life-threatening thromboembolic attack during follow-up. Blood Coagul Fibrinolysis 23:69-70 (C) 2011 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.

引用

页码：69 / 70

页数：2

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