Impact of Mechanical Circulatory Support on Exercise Capacity in Patients With Advanced Heart Failure

被引：1

作者：

Huang, Janice ^{[1
]}

McDonnell, Barry J. ^{[2
]}

Lawley, Justin S. ^{[3
]}

Byrd, Jessica ^{[1
]}

Stohr, Eric J. ^{[4
,5
]}

Cornwell, William K., III ^{[1
,6
]}

机构：

[1] Univ Colorado Anschutz Med Campus, Dept Med Cardiol, 12631 E 17th Ave B130,Off 7107, Aurora, CO 80045 USA

[2] Cardiff Metropolitan Univ, Sch Sport & Hlth Sci, Cardiff, Wales

[3] Univ Innsbruck, Dept Sport Sci, Innsbruck, Austria

[4] Leibniz Univ Hannover, Inst Sport Sci, Fac Philosoph Sci, Hannover, Germany

[5] Columbia Univ, Irving Med Ctr, Div Cardiol, Dept Med, New York, NY USA

[6] Univ Colorado Anschutz Med Campus, Clin Translat Res Ctr, Aurora, CO USA

来源：

EXERCISE AND SPORT SCIENCES REVIEWS | 2022年 / 50卷 / 04期

基金：

美国国家卫生研究院;

关键词：

heart failure with reduced ejection fraction; left ventricular assist device; maximal oxygen uptake; oxygen cascade; exercise intolerance; VENTRICULAR ASSIST DEVICE; IMPROVES FUNCTIONAL-CAPACITY; BLOOD-FLOW; CARDIAC TRANSPLANTATION; INTERNATIONAL-SOCIETY; LUNG-TRANSPLANTATION; SUBMAXIMAL EXERCISE; OXYGEN-TRANSPORT; AMERICAN-COLLEGE; MANAGEMENT;

D O I：

10.1249/JES.0000000000000303

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

Approximately 6 million individuals have heart failure in the United States alone and 15 million in Europe. Left ventricular assist devices (LVAD) improve survival in these patients, but functional capacity may not fully improve. This article examines the hypothesis that patients supported by LVAD experience persistent reductions in functional capacity and explores mechanisms accounting for abnormalities in exercise tolerance.

引用

页码：222 / 229

页数：8

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