Understanding how Victoria, Australia gained control of its second COVID-19 wave

被引:22
|
作者
Trauer, James M. [1 ]
Lydeamore, Michael J. [2 ,3 ]
Dalton, Gregory W. [3 ]
Pilcher, David [1 ]
Meehan, Michael T. [4 ]
McBryde, Emma S. [4 ]
Cheng, Allen C. [1 ,3 ]
Sutton, Brett [3 ]
Ragonnet, Romain [1 ]
机构
[1] Monash Univ, Sch Publ Hlth & Prevent Med, Melbourne, Vic, Australia
[2] Monash Univ, Cent Clin Sch, Melbourne, Vic, Australia
[3] Govt Victoria, Victorian Dept Hlth, Melbourne, Vic, Australia
[4] James Cook Univ, Australian Inst Trop Hlth & Med, Townsville, Qld, Australia
基金
英国医学研究理事会;
关键词
D O I
10.1038/s41467-021-26558-4
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The state of Victoria, Australia experienced a substantial second wave of COVID-19 but brought it under control with strict non-pharmaceutical interventions. Here, the authors model the second wave in Victoria to estimate the impacts of the different interventions. During 2020, Victoria was the Australian state hardest hit by COVID-19, but was successful in controlling its second wave through aggressive policy interventions. We calibrated a detailed compartmental model of Victoria's second wave to multiple geographically-structured epidemic time-series indicators. We achieved a good fit overall and for individual health services through a combination of time-varying processes, including case detection, population mobility, school closures, physical distancing and face covering usage. Estimates of the risk of death in those aged >= 75 and of hospitalisation were higher than international estimates, reflecting concentration of cases in high-risk settings. We estimated significant effects for each of the calibrated time-varying processes, with estimates for the individual-level effect of physical distancing of 37.4% (95%CrI 7.2-56.4%) and of face coverings of 45.9% (95%CrI 32.9-55.6%). That the multi-faceted interventions led to the dramatic reversal in the epidemic trajectory is supported by our results, with face coverings likely particularly important.
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页数:10
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