GERMLINE MODIFICATION USING MOUSE SPERMATOGONIAL STEM CELLS

被引：23
|
作者：
Kanatsu-Shinohara, Mito [1 ]
Shinohara, Takashi [1 ]
机构：
[1] Kyoto Univ, Dept Mol Genet, Grad Sch Med, Kyoto, Japan
来源：
METHODS IN ENZYMOLOGY, VOL 477: GUIDE TO TECHNIQUES IN MOUSE DEVELOPMENT, PART B: MOUSE MOLECULAR GENETICS, SECOND EDITION | 2010年 / 477卷
关键词：
LONG-TERM PROLIFERATION; MEDIATED GENE DELIVERY; KNOCKOUT MICE; IN-VITRO; TRANSPLANTATION; SPERMATOGENESIS; TRANSMISSION; TRANSDUCTION; GENERATION; GROWTH;
D O I：
10.1016/S0076-6879(10)77002-6
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Spermatogonial stem cells (SSCs) in the testes are a new target for germline modification. With the development of an in vitro culture system and spermatogonial transplantation technique, SSCs can now be manipulated and used as an alternative to embryonic stem cells for knockout mice production. The genetic and epigenetic stability of SSCs provide new possibilities for the application of germline mutagenesis in a wide range of animals.
引用
收藏
页码：17 / 36
页数：20
相关论文
共 50 条
  • [41] Spermatogonial stem cells
    Oatley, Jon M.
    Brinster, Ralph L.
    ADULT STEM CELLS, 2006, 419 : 259 - 282
  • [42] Efficient generation of transgenic rats through the male germline using lentiviral transduction and transplantation of spermatogonial stem cells
    Ryu, Buom-Yong
    Orwig, Kyle E.
    Oatley, Jon M.
    Lin, Chih-Cheng
    Chang, Lung-Ji
    Avarbock, Mary R.
    Brinster, Ralph L.
    JOURNAL OF ANDROLOGY, 2007, 28 (02): : 353 - 360
  • [43] Spermatogonial stem cells
    Naito, Mitsuru
    AVIAN BIOLOGY RESEARCH, 2011, 4 (02) : 66 - 69
  • [44] Spermatogonial stem cells
    Kubota, Hiroshi
    Brinster, Ralph L.
    BIOLOGY OF REPRODUCTION, 2018, 99 (01) : 52 - 74
  • [45] Spermatogonial stem cells
    de Rooij, DG
    Grootegoed, JA
    CURRENT OPINION IN CELL BIOLOGY, 1998, 10 (06) : 694 - 701
  • [46] Conversion of adult mouse unipotent germline stem cells into pluripotent stem cells
    Kinarm Ko
    Marcos J Araúzo-Bravo
    Julee Kim
    Martin Stehling
    Hans R Schöler
    Nature Protocols, 2010, 5 : 921 - 928
  • [47] Conversion of adult mouse unipotent germline stem cells into pluripotent stem cells
    Ko, Kinarm
    Arauzo-Bravo, Marcos J.
    Kim, Julee
    Stehling, Martin
    Schoeler, Hans R.
    NATURE PROTOCOLS, 2010, 5 (05) : 921 - 928
  • [48] Human spermatogonial stem cells display limited proliferation in vitro under mouse spermatogonial stem cell culture conditions
    Medrano, Jose V.
    Rombaut, Charlotte
    Simon, Carlos
    Pellicer, Antonio
    Goossens, Ellen
    FERTILITY AND STERILITY, 2016, 106 (06) : 1539 - +
  • [49] Oocyte-like cells induced from mouse spermatogonial stem cells
    Wang, Lu
    Cao, Jinping
    Ji, Ping
    Zhang, Di
    Ma, Lianghong
    Dym, Martin
    Yu, Zhuo
    Feng, Lixin
    CELL AND BIOSCIENCE, 2012, 2
  • [50] Three-Dimensional Culture of Mouse Spermatogonial Stem Cells Using A Decellularised Testicular Scaffold
    Gharenaz, Nasrin Majidi
    Movahedin, Mansoureh
    Mazaheri, Zohreh
    CELL JOURNAL, 2020, 21 (04) : 410 - 418
12345