Macrophages and Dendritic Cells for Treating Kidney Disease

被引：12
|
作者：
Cao, Q. [1 ]
Zheng, D. [1 ]
Wang, Y. P. [1 ]
Harris, D. C. H. [1 ]
机构：
[1] Univ Sydney, Westmead Millennium Inst, Ctr Transplantat & Renal Res, Westmead, NSW 2145, Australia
来源：
NEPHRON EXPERIMENTAL NEPHROLOGY | 2011年 / 117卷 / 03期
关键词：
Macrophages; Dendritic cells; Renal architecture; EXPERIMENTAL GLOMERULONEPHRITIS; EXPRESSION; INFLAMMATION; NEPHRITIS; INJURY; VIVO;
D O I：
10.1159/000320595
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
Based on new understanding of the diverse biological functions of macrophages and dendritic cells (DC), the focus of studies on these cells has been expanded from their pathogenic role in renal diseases to include their potential to regulate inflammation and restore renal architecture and function. By exploiting their regulatory function, macrophages or DC have been used to treat experimental renal disease following their adoptive transfer. This review summarizes current progress in the therapeutic use of macrophages and DC in renal diseases. Key issues for ongoing research are discussed. Copyright (C) 2010 S. Karger AG, Basel
引用
收藏
页码：E47 / E52
页数：6
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