Macrophages and Dendritic Cells for Treating Kidney Disease

被引：12

作者：

Cao, Q. ^{[1
]}

Zheng, D. ^{[1
]}

Wang, Y. P. ^{[1
]}

Harris, D. C. H. ^{[1
]}

机构：

[1] Univ Sydney, Westmead Millennium Inst, Ctr Transplantat & Renal Res, Westmead, NSW 2145, Australia

来源：

NEPHRON EXPERIMENTAL NEPHROLOGY | 2011年 / 117卷 / 03期

关键词：

Macrophages; Dendritic cells; Renal architecture; EXPERIMENTAL GLOMERULONEPHRITIS; EXPRESSION; INFLAMMATION; NEPHRITIS; INJURY; VIVO;

D O I：

10.1159/000320595

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Based on new understanding of the diverse biological functions of macrophages and dendritic cells (DC), the focus of studies on these cells has been expanded from their pathogenic role in renal diseases to include their potential to regulate inflammation and restore renal architecture and function. By exploiting their regulatory function, macrophages or DC have been used to treat experimental renal disease following their adoptive transfer. This review summarizes current progress in the therapeutic use of macrophages and DC in renal diseases. Key issues for ongoing research are discussed. Copyright (C) 2010 S. Karger AG, Basel

引用

页码：E47 / E52

页数：6

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