IMMUNODEFICIENCY VIRUSES;
GROUP-O;
GROUP N;
IDENTIFICATION;
PREVALENCE;
GORILLAS;
D O I:
10.1128/JVI.02005-10
中图分类号:
Q93 [微生物学];
学科分类号:
071005 ;
100705 ;
摘要:
We report the second human immunodeficiency virus (HIV) belonging to the new HIV type 1 (HIV-1) group P lineage that is closely related to the simian immunodeficiency virus found in gorillas. This virus was identified in an HIV-seropositive male hospital patient in Cameroon, confirming that the group P virus is circulating in humans. Results from screening 1,736 HIV-seropositive specimens collected in Cameroon indicate that HIV-1 group P infections are rare, accounting for only 0.06% of HIV infections. Despite its rarity, group P shows evidence of adaptation to humans.
机构:
Univ Cape Town, Int Ctr Genet Engn & Biotechnol, ZA-7925 Cape Town, South Africa
Inst Med Res & Study Med Plant IMPM, Yaounde, CameroonUniv Cape Town, Int Ctr Genet Engn & Biotechnol, ZA-7925 Cape Town, South Africa
Tongo, Marcel
Burgers, Wendy A.
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机构:
Univ Cape Town, IDM, ZA-7925 Cape Town, South AfricaUniv Cape Town, Int Ctr Genet Engn & Biotechnol, ZA-7925 Cape Town, South Africa
Burgers, Wendy A.
Abrahams, Melissa-Rose
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机构:
Univ Cape Town, IDM, ZA-7925 Cape Town, South AfricaUniv Cape Town, Int Ctr Genet Engn & Biotechnol, ZA-7925 Cape Town, South Africa
Abrahams, Melissa-Rose
Martin, Darren P.
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机构:
Univ Cape Town, IDM, ZA-7925 Cape Town, South AfricaUniv Cape Town, Int Ctr Genet Engn & Biotechnol, ZA-7925 Cape Town, South Africa
机构:
CHU Charles Nicolle, Virol Unit, Equipe Daccueil 2636, Lab Associe,Ctr Natl Reference VIH, F-76031 Rouen, FranceCHU Charles Nicolle, Virol Unit, Equipe Daccueil 2636, Lab Associe,Ctr Natl Reference VIH, F-76031 Rouen, France
Plantier, JC
Lemée, W
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机构:CHU Charles Nicolle, Virol Unit, Equipe Daccueil 2636, Lab Associe,Ctr Natl Reference VIH, F-76031 Rouen, France
Lemée, W
Dorval, L
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机构:CHU Charles Nicolle, Virol Unit, Equipe Daccueil 2636, Lab Associe,Ctr Natl Reference VIH, F-76031 Rouen, France
Dorval, L
Gueudin, M
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h-index: 0
机构:CHU Charles Nicolle, Virol Unit, Equipe Daccueil 2636, Lab Associe,Ctr Natl Reference VIH, F-76031 Rouen, France
Gueudin, M
Braun, J
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机构:CHU Charles Nicolle, Virol Unit, Equipe Daccueil 2636, Lab Associe,Ctr Natl Reference VIH, F-76031 Rouen, France
Braun, J
Hutin, P
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h-index: 0
机构:CHU Charles Nicolle, Virol Unit, Equipe Daccueil 2636, Lab Associe,Ctr Natl Reference VIH, F-76031 Rouen, France
Hutin, P
Ruffault, A
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机构:CHU Charles Nicolle, Virol Unit, Equipe Daccueil 2636, Lab Associe,Ctr Natl Reference VIH, F-76031 Rouen, France
Ruffault, A
Simon, F
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h-index: 0
机构:CHU Charles Nicolle, Virol Unit, Equipe Daccueil 2636, Lab Associe,Ctr Natl Reference VIH, F-76031 Rouen, France
机构:
CHU Rouen, Hop Charles Nicolle, Virol Lab, Ctr Natl Reference VIH, F-76031 Rouen, France
Univ Rouen, GRAM EA2656, Fac Med Pharm, Rouen, FranceCHU Rouen, Hop Charles Nicolle, Virol Lab, Ctr Natl Reference VIH, F-76031 Rouen, France
Alessandri-Gradt, Elodie
Morgand, Marjolaine
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h-index: 0
机构:
Univ Paris Diderot, Hop Lariboisiere, AP HP, Sorbonne Paris Cite,Serv Med Interne A, Paris, FranceCHU Rouen, Hop Charles Nicolle, Virol Lab, Ctr Natl Reference VIH, F-76031 Rouen, France
Morgand, Marjolaine
Delaugerre, Constance
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h-index: 0
机构:
Univ Paris Diderot, Hop St Louis, AP HP, Virol Lab,Sorbonne Paris Cite, Paris, France
Hop St Louis, INSERM U941, Paris, FranceCHU Rouen, Hop Charles Nicolle, Virol Lab, Ctr Natl Reference VIH, F-76031 Rouen, France
Delaugerre, Constance
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机构:
Peytavin, Gilles
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机构:
Sellier, Pierre
Simon, Francois
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h-index: 0
机构:
Hop St Louis, INSERM U941, Paris, FranceCHU Rouen, Hop Charles Nicolle, Virol Lab, Ctr Natl Reference VIH, F-76031 Rouen, France
机构:
Univ So Calif, Keck Sch Med, Dept Mol Microbiol & Immunol, Los Angeles, CA 90033 USAUniv So Calif, Keck Sch Med, Dept Mol Microbiol & Immunol, Los Angeles, CA 90033 USA
Yang, Su Jung
Lopez, Lisa A.
论文数: 0引用数: 0
h-index: 0
机构:
Univ So Calif, Keck Sch Med, Dept Mol Microbiol & Immunol, Los Angeles, CA 90033 USAUniv So Calif, Keck Sch Med, Dept Mol Microbiol & Immunol, Los Angeles, CA 90033 USA
Lopez, Lisa A.
Exline, Colin M.
论文数: 0引用数: 0
h-index: 0
机构:
Univ So Calif, Keck Sch Med, Dept Mol Microbiol & Immunol, Los Angeles, CA 90033 USAUniv So Calif, Keck Sch Med, Dept Mol Microbiol & Immunol, Los Angeles, CA 90033 USA
Exline, Colin M.
Haworth, Kevin G.
论文数: 0引用数: 0
h-index: 0
机构:
Univ So Calif, Keck Sch Med, Dept Mol Microbiol & Immunol, Los Angeles, CA 90033 USAUniv So Calif, Keck Sch Med, Dept Mol Microbiol & Immunol, Los Angeles, CA 90033 USA
Haworth, Kevin G.
Cannon, Paula M.
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h-index: 0
机构:
Univ So Calif, Keck Sch Med, Dept Mol Microbiol & Immunol, Los Angeles, CA 90033 USAUniv So Calif, Keck Sch Med, Dept Mol Microbiol & Immunol, Los Angeles, CA 90033 USA