Confirmation of Putative HIV-1 Group P in Cameroon

被引：89
|
作者：
Vallari, Ana
Holzmayer, Vera
Harris, Barbara
Yamaguchi, Julie
Ngansop, Charlotte [2 ]
Makamche, Florence [2 ]
Mbanya, Dora [2 ]
Kaptue, Lazare [2 ,3 ]
Ndembi, Nicaise [2 ,4 ]
Guertler, Lutz [5 ]
Devare, Sushil
Brennan, Catherine A. [1 ]
机构：
[1] Abbott Diagnost, Dept 09NG, Abbott Pk, IL 60064 USA
[2] Univ Yaounde 1, Yaounde, Cameroon
[3] Univ Montagnes, Bangangte, Cameroon
[4] Inst Human Virol, Abuja, Nigeria
[5] Univ Munich, Max Von Pettenkofer Inst, Munich, Germany
来源：
JOURNAL OF VIROLOGY | 2011年 / 85卷 / 03期
关键词：
IMMUNODEFICIENCY VIRUSES; GROUP-O; GROUP N; IDENTIFICATION; PREVALENCE; GORILLAS;
D O I：
10.1128/JVI.02005-10
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
We report the second human immunodeficiency virus (HIV) belonging to the new HIV type 1 (HIV-1) group P lineage that is closely related to the simian immunodeficiency virus found in gorillas. This virus was identified in an HIV-seropositive male hospital patient in Cameroon, confirming that the group P virus is circulating in humans. Results from screening 1,736 HIV-seropositive specimens collected in Cameroon indicate that HIV-1 group P infections are rare, accounting for only 0.06% of HIV infections. Despite its rarity, group P shows evidence of adaptation to humans.
引用
收藏
页码：1403 / 1407
页数：5
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