High-resolution melting assay for genotyping of IFNL4-associated dinucleotide variant rs368234815

被引：2
|
作者：
Galmozzi, E. [1 ]
Facchetti, F. [1 ]
Perbellini, R. [1 ]
Aghemo, A. [1 ]
机构：
[1] Univ Milan, Fdn IRCCS Ca Granda Osped Maggiore Policlin, Div Gastroenterol & Hepatol, Milan, Italy
来源：
CLINICAL MICROBIOLOGY AND INFECTION | 2014年 / 20卷 / 11期
关键词：
hepatitis C virus; high-resolution melting; IFNL4; IL28B; RT-PCR; PEGYLATED INTERFERON-ALPHA; HEPATITIS-C; SPONTANEOUS CLEARANCE; GENETIC-VARIATION; IL28B; POLYMORPHISM; ASSOCIATION; RIBAVIRIN; THERAPY; ALLELE;
D O I：
10.1111/1469-0691.12637
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Interferon-4-related dinucleotide variant rs368234815 TT/-G is strongly linked with rs12979860 polymorphism, the most important genetic marker connected to treatment-induced hepatitis C virus clearance. Due to additional baseline information that rs368234815 polymorphism could provide for the management of chronic hepatitis C, we developed and validated a high-resolution melting genotyping assay using 193 patients with chronic hepatitis C.
引用
收藏
页码：O936 / O938
页数：3
相关论文
共 36 条
  • [31] GENOTYPING OF GATA4 GENE VARIANT (G296S) IN MALAYSIAN CONGENITAL HEART DISEASE SUBJECTS BY REAL-TIME PCR HIGH RESOLUTION MELTING ANALYSIS
    Fawzi, Nora
    Vasudevan, Ramachandran
    Ismail, Patimah
    Alwi, Mazeni
    Aziz, Ahmad Fazli Abdul
    Almeamar, Hussein
    Mohamad, Nur Afiqa
    Etemad, Ali
    JOURNAL OF MEDICAL BIOCHEMISTRY, 2013, 32 (02) : 152 - 157
  • [32] A rapid screening assay for L452R and T478K spike mutations in SARS-CoV 2 Delta variant using high-resolution melting analysis
    Aoki, Akira
    Adachi, Hirokazu
    Mori, Yoko
    Ito, Miyabi
    Sato, Katsuhiko
    Okuda, Kenji
    Sakakibara, Toru
    Okamoto, Yoshinori
    Jinno, Hideto
    JOURNAL OF TOXICOLOGICAL SCIENCES, 2021, 46 (10): : 471 - 476
  • [33] Collagen type III alpha 1 polymorphism (rs1800255, COL3A1 2209 G>A) assessed with high-resolution melting analysis is not associated with pelvic organ prolapse in the Dutch population
    Sabrina L. Lince
    Leon C. van Kempen
    Jeroen R. Dijkstra
    Joanna IntHout
    Mark E. Vierhout
    Kirsten B. Kluivers
    International Urogynecology Journal, 2014, 25 : 1237 - 1242
  • [34] Real-time RT-PCR high-resolution melting curve analysis and multiplex RT-PCR to detect and differentiate grapevine leafroll-associated associated virus 3 variant groups I, II, III and VI
    Bester, Rachelle
    Jooste, Anna E. C.
    Maree, Hans J.
    Burger, Johan T.
    VIROLOGY JOURNAL, 2012, 9
  • [35] Collagen type III alpha 1 polymorphism (rs1800255, COL3A1 2209 G>A) assessed with high-resolution melting analysis is not associated with pelvic organ prolapse in the Dutch population
    Lince, Sabrina L.
    van Kempen, Leon C.
    Dijkstra, Jeroen R.
    IntHout, Joanna
    Vierhout, Mark E.
    Kluivers, Kirsten B.
    INTERNATIONAL UROGYNECOLOGY JOURNAL, 2014, 25 (09) : 1237 - 1242
  • [36] Real-time RT-PCR high-resolution melting curve analysis and multiplex RT-PCR to detect and differentiate grapevine leafroll-associated virus 3 variant groups I, II, III and VI
    Rachelle Bester
    Anna E C Jooste
    Hans J Maree
    Johan T Burger
    Virology Journal, 9
1234