Therapeutic vaccine JNJ-0535 induces a strong HBV-specific T-cell response in healthy adults and a modest response in chronic HBV-infected patients

被引：0

作者：

De Creus, An ^{[1
]}

Slaets, Leen ^{[1
]}

Fevery, Bart ^{[1
]}

Van Gulck, Ellen ^{[1
]}

Zhou, Linghua ^{[1
]}

Van De Parre, Tim ^{[1
]}

Van Den Broeke, Celine ^{[1
]}

Dimitrova, Dessislava ^{[2
]}

Lonjon-Domanec, Isabelle ^{[1
]}

Blue, David, Jr. ^{[3
]}

Van Remoortere, Pieter ^{[2
]}

Bourgeois, Stefan ^{[4
]}

Kennedy, Patrick ^{[5
]}

De Meyer, Sandra

机构：

[1] Janssen Res & Dev, Beerse, Belgium

[2] Janssen Res & Dev, Raritan, NJ 08869 USA

[3] Janssen Biopharma Inc, Horsham, PA USA

[4] Hosp Network Antwerp ZNA, Antwerp, Belgium

[5] Barts & London Queen Marys Sch Med & Dent, London, England

来源：

JOURNAL OF HEPATOLOGY | 2022年 / 77卷

关键词：

D O I：

暂无

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

OS094

引用

页码：S72 / S73

页数：2

共 26 条

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[2] HBV-SPECIFIC PROLIFERATIVE T CELL RESPONSE IS NOT RESTORED BY THERAPEUTIC HBV SUPPRESSION OR CORRELATE WITH HBsAg TITER
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HEPATOLOGY, 2022, 76 : S29 - S30
[3] Diverse facets of MDSC in different phases of chronic HBV infection: Impact on HBV-specific T-cell response and homing
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[4] Skewed repertoire of HBV-specific CD8 T cell response in chronic HBV infection
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[5] Skewed repertoire of HBV-specific CD8 T cell response in chronic HBV infection.
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HEPATOLOGY, 2002, 36 (04) : 607A - 607A
[6] HEPATITIS-B VIRUS (HBV)-SPECIFIC T-CELL RESPONSE IN CHRONIC HBV INFECTION
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JOURNAL OF CELLULAR BIOCHEMISTRY, 1995, : 291 - 291
[7] HDV- AND HBV-SPECIFIC T CELL RESPONSE PATTERNS IN PATIENTS WITH DELTA HEPATITIS
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[8] The role of the virus specific T-Cell response in acute and chronic HBV and HCV infection
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[9] HBV-SPECIFIC T CELL RESPONSE OF HCV-INFECTED PATIENTS WITH ISOLATED ANTI-HBC AND COMBINED ANTI-HBC/ANTI-HBS ANTIBODY RESPONSE
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HEPATOLOGY, 2010, 52 (04) : 980A - 981A
[10] Combined GS-4774 and Tenofovir Therapy Can Improve HBV-Specific T-Cell Responses in Patients With Chronic Hepatitis
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GASTROENTEROLOGY, 2019, 157 (01) : 227 - +

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