Role of aqueous medium in mechanisms underlying the influence of immunoactive peptides in ultralow doses

被引：4
|
作者：
Grigor'ev, EI [1 ]
Khavinson, VK [1 ]
Malinin, VV [1 ]
Grigor'ev, AE [1 ]
Kudryavtseva, TA [1 ]
机构：
[1] Russian Acad Med Sci, St Petersburg Inst Bioregulat & Gerontol, Northwestern Div, St Petersburg, Russia
来源：
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2003年 / 136卷 / 02期
关键词：
ultralow doses; peptides; signal transduction; solitons; infrared spectroscopy;
D O I：
10.1023/A:1026362706175
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
The mechanism underlying the influence of peptides in ultralow doses is based on distant signal transduction from the ligand molecules to target cells by means of water solitons. Biological activity of synthetic immunoactive peptides in concentrations below 10(-18) M depends on their structural and conformational characteristics. The data on temperature dependencies of the near-infrared spectrum for solutions of these peptides are presented.
引用
收藏
页码：150 / 154
页数：5
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