One-Pot Synthesis of 2,3-Disubstituted-2,3-dihydroquinazolin-4(1H)-ones Using [Hmim][NO3]: An Eco-Friendly Protocol

被引：7
|
作者：
Mohammadpoor-Baltork, Iraj [1 ]
Khosropour, Ahmad Reza [1 ]
Moghadam, Majid [1 ]
Tangestaninejad, Shahram [1 ]
Mirkhani, Valiollah [1 ]
Soltani, Mohammad [1 ]
Mirjafari, Arsalan [1 ]
机构：
[1] Univ Isfahan, Dept Chem, Catalysis Div, Esfahan 817467344, Iran
来源：
JOURNAL OF HETEROCYCLIC CHEMISTRY | 2011年 / 48卷 / 06期
关键词：
IONIC LIQUIDS; ISATIS-INDIGOTICA; DERIVATIVES; QUINAZOLINE; INHIBITION; ALKALOIDS; 2,3-DIHYDROQUINAZOLIN-4(1H)-ONES; QUINAZOLIN-4(3H)-ONES; ISAINDIGOTONE; PLASTICIZERS;
D O I：
10.1002/jhet.721
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient method for the synthesis of a series of 2,3-disubstituted-2,3-dihydroquinazolin-4(1H)-ones is described via one-pot condensation reaction of isatoic anhydride, aryl aldehydes, and primary amines using a Bronsted acidic ionic liquid, [Hmim][NO3], as a catalyst and medium. The present protocol enjoys convenient reaction and simple work-up, greenness, short reaction times, and reusable catalyst as well as mild reaction conditions.
引用
收藏
页码：1419 / 1427
页数：9
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