Hepatocyte growth factor in nephronophthisis-medullary cystic disease complex

被引:4
|
作者
Yorioka, N
Taniguchi, Y
Yamashita, K
Usui, K
Shigemoto, K
Harada, S
Taguchi, T
Yamakido, M
机构
[1] Second Department of Internal Medicine, Hiroshima University, School of Medicine, Hiroshima
[2] Ichiyokai Harada Hospital, Hiroshima
[3] Second Department of Pathology, Nagasaki University, School of Medicine, Nagasaki
[4] Second Department of Internal Medicine, Hiroshima University, School of Medicine, Minami-ku, Hiroshima, 734
关键词
nephronophthisis-medullary cystic disease complex; cyst transformation; hepatocyte growth factor; immunohistochemistry;
D O I
10.1007/s004670050154
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
A 13-year-old Japanese girl presented with severe anemia and renal dysfunction. The nephronophthisis-medullary cystic disease complex was diagnosed from the results of renal biopsy and a family study. Immunohistochemical detection of hepatocyte growth factor in the epithelial cells of dilated renal tubules suggested that it may have a role in the development of the tubular cystic changes which are characteristic of this disease.
引用
收藏
页码:515 / 516
页数:2
相关论文
共 50 条
  • [31] NEPHRONOPHTHISIS (MEDULLARY CYSTIC-DISEASE OF THE KIDNEY) - A STUDY USING ELECTRON-MICROSCOPY, IMMUNOFLUORESCENCE, AND A REVIEW OF THE MORPHOLOGICAL FINDINGS
    ZOLLINGER, HU
    MIHATSCH, MJ
    EDEFONTI, A
    GABOARDI, F
    IMBASCIATI, E
    LENNERT, T
    HELVETICA PAEDIATRICA ACTA, 1980, 35 (06) : 509 - 530
  • [32] A GENE FOR FAMILIAL JUVENILE NEPHRONOPHTHISIS (RECESSIVE MEDULLARY CYSTIC KIDNEY-DISEASE) MAPS TO CHROMOSOME-2P
    ANTIGNAC, C
    ARDUY, CH
    BECKMANN, JS
    BENESSY, F
    GROS, F
    MEDHIOUB, M
    HILDEBRANDT, F
    DUFIER, JL
    KLEINKNECHT, C
    BROYER, M
    WEISSENBACH, J
    HABIB, R
    COHEN, D
    NATURE GENETICS, 1993, 3 (04) : 342 - 345
  • [33] Sonographic appearance of the juvenile nephronophthisis cystic renal medulla complex
    Aguilera, A
    Rivera, M
    Gallego, N
    Nogueira, J
    Ortuno, J
    NEPHROLOGY DIALYSIS TRANSPLANTATION, 1997, 12 (03) : 625 - 626
  • [34] RENAL MEDULLARY CYSTIC DISEASE
    SPICER, RD
    OGG, CS
    SAXTON, HM
    CAMERON, JS
    BRITISH MEDICAL JOURNAL, 1969, 1 (5647): : 824 - &
  • [35] Hepatocyte growth factor and vascular endothelial growth factor in ischaemic heart disease
    Suzuki, H
    Murakami, M
    Shoji, M
    Iso, Y
    Kondo, T
    Shibata, M
    Ezumi, H
    Hamazaki, Y
    Koba, S
    Katagiri, T
    CORONARY ARTERY DISEASE, 2003, 14 (04) : 301 - 307
  • [36] Expression of hepatocyte growth factor (HGF) and its receptor (MET) in medullary carcinoma of the thyroid
    Mauro Papotti
    Martina Olivero
    Marco Volante
    Francesco Negro
    Maria Prat
    Paolo M. Comoglio
    Maria Flavia DiRenzo
    Endocrine Pathology, 2000, 11 : 19 - 30
  • [37] Expression of hepatocyte growth factor (HGF) and its receptor (MET) in medullary carcinoma of the thyroid
    Papotti, M
    Olivero, M
    Volante, M
    Negro, F
    Prat, M
    Comoglio, PM
    DiRenzo, MF
    ENDOCRINE PATHOLOGY, 2000, 11 (01) : 19 - 30
  • [38] RENAL MEDULLARY CYSTIC DISEASE (MEDULLARY SPONGE KIDNEY)
    SANERKIN, NG
    JOURNAL OF CLINICAL PATHOLOGY, 1965, 18 (01) : 121 - &
  • [39] Hepatocyte growth factor (HGF) and proliferative vitreoretinal disease
    Heathcote, LE
    Grierson, I
    Hiscott, P
    Wong, D
    Groenewald, C
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2003, 44 : U89 - U89
  • [40] Hepatocyte growth factor in renal disease: cause or cure?
    N. J. Laping
    Cellular and Molecular Life Sciences CMLS, 1999, 56 : 371 - 377