Hepatocyte growth factor in nephronophthisis-medullary cystic disease complex

被引:4
|
作者
Yorioka, N
Taniguchi, Y
Yamashita, K
Usui, K
Shigemoto, K
Harada, S
Taguchi, T
Yamakido, M
机构
[1] Second Department of Internal Medicine, Hiroshima University, School of Medicine, Hiroshima
[2] Ichiyokai Harada Hospital, Hiroshima
[3] Second Department of Pathology, Nagasaki University, School of Medicine, Nagasaki
[4] Second Department of Internal Medicine, Hiroshima University, School of Medicine, Minami-ku, Hiroshima, 734
关键词
nephronophthisis-medullary cystic disease complex; cyst transformation; hepatocyte growth factor; immunohistochemistry;
D O I
10.1007/s004670050154
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
A 13-year-old Japanese girl presented with severe anemia and renal dysfunction. The nephronophthisis-medullary cystic disease complex was diagnosed from the results of renal biopsy and a family study. Immunohistochemical detection of hepatocyte growth factor in the epithelial cells of dilated renal tubules suggested that it may have a role in the development of the tubular cystic changes which are characteristic of this disease.
引用
收藏
页码:515 / 516
页数:2
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