Insulin neuroprotection against oxidative stress involves Akt/GSK-3β signalling pathways and changes in protein expressionl

被引:0
|
作者
Duarte, Ana I. [1 ]
Santos, M. Sancha [1 ]
Santos, Paulo [2 ]
Oliveira, Catarina R. [3 ]
Rego, A. Cristina [3 ]
机构
[1] Univ Coimbra, Fac Sci & Technol, Ctr Neurosci & Cell Biol, Dept Zool, Coimbra, Portugal
[2] Univ Coimbra, Ctr Histocompatibility, Coimbra, Portugal
[3] Univ Coimbra, Fac Med, Inst Biochem, Ctr Neurosci & Cell Biol, Coimbra, Portugal
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:S24 / S24
页数:1
相关论文
共 50 条
  • [21] Kukoamine A activates Akt/GSK-3β signaling pathway to inhibit oxidative stress and relieve myocardial ischemia-reperfusion injury
    Xu, Han
    Zhang, Guibin
    Deng, Long
    ACTA CIRURGICA BRASILEIRA, 2022, 37 (04)
  • [22] Kukoamine A Activates Akt/GSK-3β Pathway to Repress Oxidative Stress and Inflammation to Alleviate Myocardial Ischemia-reperfusion Injury
    Hong, Jianmao
    Ye, Yanqiong
    Zheng, Dingwen
    Qian, Ximing
    LETTERS IN DRUG DESIGN & DISCOVERY, 2024, 21 (12) : 2374 - 2383
  • [23] Remimazolam Suppresses Oxidative Stress and Apoptosis in Cerebral Ischemia/Reperfusion Injury by Regulating AKT/GSK-3(3/NRF2 Pathway
    Duan, Mei
    Yu, Ning
    Liu, Jia
    Zhao, Yang
    Zhang, Jing
    Song, Siyi
    Wang, Shilei
    DRUG DESIGN DEVELOPMENT AND THERAPY, 2025, 19 : 111 - 128
  • [24] Neuroprotection of PDGF-B against oxidative stress via the PI3K/Akt signal
    Zheng, Lianshun
    Ishii, Yoko
    Oya, Takeshi
    Tokunaga, Ayano
    Hamashima, Takeru
    Ishizawa, Shin
    Sasahara, Masakiyo
    NEUROSCIENCE RESEARCH, 2007, 58 : S150 - S150
  • [25] Potential therapeutic antipsychotic effects of Naringin against ketamineinduced deficits in rats: Involvement of Akt/GSK-3β and Wnt/β-catenin signaling pathways
    George, Mina Y.
    Menze, Esther T.
    Esmat, Ahmed
    Tadros, Mariane G.
    El-Demerdash, E.
    LIFE SCIENCES, 2020, 249
  • [26] Neuroprotection of insulin against oxidative stress-induced apoptosis in cultured retinal neurons: Involvement of phosphoinositide 3-kinase/Akt signal pathway
    Yu, XR
    Jia, GR
    Gao, GD
    Wang, SH
    Han, Y
    Cao, W
    ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2006, 38 (04) : 241 - 248
  • [27] Substance P promotes the recovery of oxidative stress-damaged retinal pigmented epithelial cells by modulating Akt/GSK-3β signaling
    Baek, Sang-Min
    Yu, Seung-Young
    Son, Youngsook
    Hong, Hyun Sook
    MOLECULAR VISION, 2016, 22 : 1015 - 1023
  • [28] Penehyclidine hydrochloride protects against anoxia/reoxygenation injury in cardiomyocytes through ATP-sensitive potassium channels, and the Akt/GSK-3β and Akt/mTOR signaling pathways
    Zi, Congna
    Zhang, Chunlei
    Yang, Yanli
    Ma, Jun
    CELL BIOLOGY INTERNATIONAL, 2020, 44 (06) : 1353 - 1362
  • [29] The Cytoprotective Effect of Hyperoside against Oxidative Stress Is Mediated by the Nrf2-ARE Signaling Pathway through GSK-3β Inactivation
    Xing, Hai-Yan
    Cai, Yong-Qing
    Wang, Xian-Feng
    Wang, Lin-Li
    Li, Pan
    Wang, Guan-Ying
    Chen, Jian-Hong
    PLOS ONE, 2015, 10 (12):
  • [30] Neuroprotection by Ginsenoside Rg1 against beta-amyloid-induced apoptosis is mediated by PI-3K/Akt/GSK-3 beta signaling pathway
    Zhang, J.
    Tu, Z.
    JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2009, 57 : S56 - S56