Toll and Toll-like receptors in Drosophila

被引：29

作者：

Bilak, H ^{[1
]}

Tauszig-Delamasure, S ^{[1
]}

Imler, JL ^{[1
]}

机构：

[1] CNRS, UPR9022, F-67084 Strasbourg, France

来源：

BIOCHEMICAL SOCIETY TRANSACTIONS | 2003年 / 31卷

关键词：

bacterial infection; fruit fly; innate immunity; signal transduction;

D O I：

10.1042/bst0310648

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The Drosophila Toll receptor controls the immune response to Gram-positive bacteria and fungi by activating a signalling pathway partially conserved throughout evolution. The Drosophila genome encodes eight additional Toll-related receptors, most of which appear to carry out developmental rather than immune functions. one exception may be Toll-9, which shares structural and functional similarities with mammalian TLRs.

引用

页码：648 / 651

页数：4

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