Toll and Toll-like receptors in Drosophila

被引：29
|
作者：
Bilak, H [1 ]
Tauszig-Delamasure, S [1 ]
Imler, JL [1 ]
机构：
[1] CNRS, UPR9022, F-67084 Strasbourg, France
来源：
BIOCHEMICAL SOCIETY TRANSACTIONS | 2003年 / 31卷
关键词：
bacterial infection; fruit fly; innate immunity; signal transduction;
D O I：
10.1042/bst0310648
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The Drosophila Toll receptor controls the immune response to Gram-positive bacteria and fungi by activating a signalling pathway partially conserved throughout evolution. The Drosophila genome encodes eight additional Toll-related receptors, most of which appear to carry out developmental rather than immune functions. one exception may be Toll-9, which shares structural and functional similarities with mammalian TLRs.
引用
收藏
页码：648 / 651
页数：4
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