Virus Isolation from the First Patient with SARS-CoV-2 in Korea

被引：127

作者：

Park, Wan Beom ^{[1
,2
]}

Kwon, Nak-Jung ^{[3
]}

Choi, Su-Jin ^{[2
]}

Kang, Chang Kyung ^{[1
]}

Choe, Pyoeng Gyun ^{[1
]}

Kim, Jin Yong ^{[4
]}

Yun, Jiyoung ^{[3
]}

Lee, Gir-Won ^{[3
]}

Seong, Moon-Woo ^{[5
]}

Kim, Nam Joong ^{[1
,2
]}

Seo, Jeong-Sun ^{[3
,6
]}

Oh, Myoung-don ^{[1
,2
]}

机构：

[1] Seoul Natl Univ, Dept Internal Med, Coll Med, 101 Daehak Ro, Seoul 03080, South Korea

[2] Seoul Natl Univ Hosp, Lab Infect & Immun, Biomed Res Inst, Seoul, South Korea

[3] Macrogen Inc, Seoul, South Korea

[4] Incheon Med Ctr, Dept Internal Med, Incheon, South Korea

[5] Seoul Natl Univ, Dept Lab Med, Coll Med, Seoul, South Korea

[6] Seoul Natl Univ, Precis Med Ctr, Bundang Hosp, Seongnam, South Korea

来源：

JOURNAL OF KOREAN MEDICAL SCIENCE | 2020年 / 35卷 / 07期

关键词：

2019 Novel Coronavirus; Culture; Microscopy; Electron; Phylogeny; Korea; CORONAVIRUS; ALIGNMENT;

D O I：

10.3346/jkms.2020.35.e84

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Novel coronavirus (SARS-CoV-2) is found to cause a large outbreak started from Wuhan since December 2019 in China and SARS-CoV-2 infections have been reported with epidemiological linkage to China in 25 countries until now. We isolated SARS-CoV-2 from the oropharyngeal sample obtained from the patient with the first laboratory-confirmed SARSCoV-2 infection in Korea. Cytopathic effects of SARS-CoV-2 in the Vero cell cultures were confluent 3 days after the first blind passage of the sample. Coronavirus was confirmed with spherical particle having a fringe reminiscent of crown on transmission electron microscopy. Phylogenetic analyses of whole genome sequences showed that it clustered with other SARS-CoV-2 reported from Wuhan.

引用

页数：5

共 50 条

[41] Coinfection with SARS-CoV-2 and influenza A virus
Kondo, Yuki
Miyazaki, Shinichi
Yamashita, Ryo
Ikeda, Takuya
BMJ CASE REPORTS, 2020, 13 (07)
[42] Immunopathology of SARS-CoV-2 virus infection
Javier Espinosa-Rosales, Francisco
ACTA PEDIATRICA DE MEXICO, 2020, 41 (04): : S42 - S50
[43] Novel Corona Virus (SARS-CoV-2)
Hoenemann, Mario
Luebbert, Christoph
Liebert, Uwe G.
DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT, 2020, 145 (05) : 336 - 337
[44] First case of postmortem study in a patient vaccinated against SARS-CoV-2
Hansen, Torsten
Titze, Ulf
Kulamadayil-Heidenreich, Nidhi Su Ann
Glombitza, Sabine
Tebbe, Johannes Josef
Roecken, Christoph
Schulz, Birte
Weise, Michael
Wilkens, Ludwig
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 2021, 107 : 172 - 175
[45] SARS-CoV-2 Pandemic: Not the First, Not the Last
Calistri, Paolo
Decaro, Nicola
Lorusso, Alessio
MICROORGANISMS, 2021, 9 (02) : 1 - 11
[46] First description of SARS-CoV-2 in ascites
Culver, Aurelien
Arbelot, Charlotte
Bechis, Carole
Cassir, Nadim
Leone, Marc
IDCASES, 2020, 21
[47] Lung cysts in a patient with SARS-CoV-2
Mariscal Aguilar, Pablo
Zamarron De Lucas, Ester
Alvarez-Sala Walther, Rodolfo
MEDICINA CLINICA, 2020, 155 (07): : 325 - 325
[48] Palatal mucormycosis in a patient with SARS-CoV-2
Venugopal, Adith
Marya, Anand
CANADIAN MEDICAL ASSOCIATION JOURNAL, 2021, 193 (37) : E1477 - E1478
[49] Thromboprophylaxis in the Sars-Cov-2 hospitalized patient
Cotrina-Pereyra, Rosa
Sisniegas-Vergara, Cesar
REVISTA DEL CUERPO MEDICO DEL HOSPITAL NACIONAL ALMANZOR AGUINAGA ASENJO, 2021, 14 (01): : 80 - 86
[50] Use of amantadine in a patient with SARS-CoV-2
Aranda-Abreu, Gonzalo Emiliano
Aranda-Martinez, Jose Dolores
Araujo, Ramiro
JOURNAL OF MEDICAL VIROLOGY, 2021, 93 (01) : 110 - 111

← 1 2 3 4 5 →