Oral Hypoglycemic Agents Added to Insulin Monotherapy for Type 2 Diabetes

被引：2

作者：

Vos, Rimke C. ^{[1
]}

Rutten, Guy E. H. M. ^{[1
]}

机构：

[1] Univ Med Ctr Utrecht, Dept Gen Practice, Julius Ctr Hlth Sci & Primary Care, Huispostnr STR 6-131,POB 85500, NL-3508 GA Utrecht, Netherlands

来源：

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION | 2017年 / 318卷 / 15期

关键词：

D O I：

10.1001/jama.2017.13463

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

CLINICAL QUESTION Among patients with type 2 diabetes mellitus who do not achieve optimal glycemic control with insulin monotherapy, is the addition of oral hypoglycemic agents associated with benefits (measured by lowering of hemoglobin A(1c)) or adverse effects? BOTTOM LINE Adding a sulfonylurea to insulin was associated with more hypoglycemic events compared with insulin alone, but this association was not observed for metformin. Adding a sulfonylurea or metformin to insulin was associated with a decrease in hemoglobin A1c of approximately 1.0%.

引用

页码：1489 / 1490

页数：2

共 50 条

[31] Glycemic Control in Patients with Type 2 Diabetes Mellitus with A1C=9.0% with Oral Hypoglycemic Agents vs. Insulin plus Oral Agents
Ortiz, Rafael Violante
Ordonez, Norma Fernandez
Gallifa, Emanuel Narvaez
Cardenas, Jose E. Guerra
Tapia, Alejandra Tavera
Reyna-Beltran, Elizabeth
Perez, Jessica Perez
Chong, Irene Castro
Garcia, Viridiana Vazquez
Grijalva, Izmene Badillo
Sanchez, Jaidy Bautista
De Leon, Karla Wong
Escobedo, Ana Olvera
Gomez, Christian Ramos
Silva, Anette Avila
DIABETES, 2024, 73
[32] Risk of Pancreatic Adenocarcinoma in Patients on Oral Hypoglycemic Agents for Type 2 Diabetes Mellitus
Babajide, Oyedotun
Desai, Aakash
Adekunle, Ayooluwatomiwa
Youssef, Michael
Sedarous, Mary
Lawendy, Bishoy
Okafor, Philip
AMERICAN JOURNAL OF GASTROENTEROLOGY, 2023, 118 (10): : S73 - S74
[33] Prediction of nocturnal hypoglycemia in patients with type 2 diabetes treated with oral hypoglycemic agents
Tan, Cuixia
He, Hua
Ma, Jing
Zhong, Li
Chen, Dawei
Wang, Chun
Liu, Guanjian
Ran, Xingwu
DIABETES-METABOLISM RESEARCH AND REVIEWS, 2017, 33
[34] Comparison of basal insulin added to oral agents versus twice-daily premixed insulin as initial insulin therapy for type 2 diabetes
Janka, HU
Kliebe-Frisch, C
Plewe, G
Schweitzer, MA
Riddle, MC
Yki-Jarvinen, H
DIABETES CARE, 2005, 28 (02) : 254 - 259
[35] ORAL HYPOGLYCEMIC AGENTS IN THE MANAGEMENT OF DIABETES
MARBLE, A
MEDICAL CLINICS OF NORTH AMERICA, 1958, 42 (05) : 1163 - 1177
[36] Type 2 diabetes quality of life patients treated with insulin and oral hypoglycemic medication
Andrzej M. Fal
Beata Jankowska
Izabella Uchmanowicz
Mariola Sen
Bernard Panaszek
Jacek Polanski
Acta Diabetologica, 2011, 48 : 237 - 242
[37] Type 2 diabetes quality of life patients treated with insulin and oral hypoglycemic medication
Fal, Andrzej M.
Jankowska, Beata
Uchmanowicz, Izabella
Sen, Mariola
Panaszek, Bernard
Polanski, Jacek
ACTA DIABETOLOGICA, 2011, 48 (03) : 237 - 242
[38] Effectiveness and Safety of Oral Hypoglycemic Agents as Initial Treatment in Comparison to Insulin Injection in Newly Diagnosed Type 2 Diabetes Mellitus
Chen, Xi
Wang, Yufan
Zhang, Aifang
Wang, Nian
Li, Na
DIABETES, 2018, 67
[39] Pharmacoeconomic simulation of delayed results of the treatment of type 2 diabetes mellitus with modern insulin analogs in comparison with oral hypoglycemic agents
Dedov, I. I.
Shestakova, M. V.
Suntsov, Yu. I.
Yagudina, R. I.
Krysanov, I. S.
Kulikov, A. Yu.
Arinina, E. E.
DIABETES MELLITUS, 2010, 13 (01): : 102 - 110
[40] Economics of basal insulin added to oral agents versus twice-daily premixed insulin as initial therapy for type 2 diabetes
Sclar, DA
Evans, MA
White, JR
Skaer, TL
Robison, LM
DIABETES, 2005, 54 : A607 - A607

← 1 2 3 4 5 →