Copper-catalyzed Markovnikov hydration of alkynes

被引：45
|
作者：
Hassam, Mohammad [1 ]
Li, Wen-Shan [1 ,2 ]
机构：
[1] Acad Sinica, Inst Chem, Taipei 115, Taiwan
[2] Natl Sun Yat Sen Univ, Doctoral Degree Program Marine Biotechnol, Kaohsiung 804, Taiwan
来源：
TETRAHEDRON | 2015年 / 71卷 / 18期
关键词：
Alkynes; Copper triflate; Hydration; Ethyl acetate; ACID; COMPLEXES; DERIVATIVES; PALLADIUM; ALCOHOLS;
D O I：
10.1016/j.tet.2015.03.034
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Conventional, highly efficient, inexpensive copper trifiate catalyzed regioselective Markovnikov hydration of terminal and internal alkynes have been reported. Significant shorter reaction time and excellent yield without addition of additive make the method attractive. Effects of catalyst and solvent on the hydration reaction have also been studied. (C) 2015 Elsevier Ltd. All rights reserved.
引用
收藏
页码：2719 / 2723
页数：5
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