A novel stereocontrolled synthesis of enantiopure bicyclic lactams

被引：8
|
作者：
Agami, C [1 ]
Dechoux, L [1 ]
Hebbe, S [1 ]
机构：
[1] Univ Paris 06, UMR 7611, Lab Synthese Asymetr, F-75005 Paris, France
来源：
TETRAHEDRON LETTERS | 2003年 / 44卷 / 28期
关键词：
beta-enaminoesters; bicyclic lactams; 3,4-dihydro-2-pyridones; oxazolidines; aza-annulation;
D O I：
10.1016/S0040-4039(03)01209-7
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A study on the reactivity of 3,4-dihydro-2-pyridones 9, derived from (S)-phenylglycinol, toward different bases is presented. Using a catalytic amount of bases, the cis bicyclic lactams were obtained with excellent diastereoselectivities. (C) 2003 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：5311 / 5313
页数：3
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