Synthesis and Antibacterial Activities of Two Novel Pyran Annulated Heterocyclic Compounds

被引:0
|
作者
Qin, Hua [1 ]
Zhang, Yan [1 ]
Wang, Ru [1 ]
机构
[1] Fourth Mil Med Univ, Tangdu Hosp, Dept Pharm, Xian 710032, Peoples R China
来源
LATIN AMERICAN JOURNAL OF PHARMACY | 2015年 / 34卷 / 03期
关键词
crystal; minimum inhibitory concentration; pyran; Staphylococcus aureus;
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Two new novel pyran annulated heterocyclic compounds (1 and 2) were synthesized and characterized via IR, H-1 NMR, HRMS, and single crystal X-ray crystallography. The in vitro antibacterial activities of the two compounds against Staphylococcus aureus (S. aureus ATCC 29213), methicillin-resistant S. aureus (MRSA XJ 75302), vancomycin-intermediate S. aureus (Mu50 ATCC 700699), and USA 300 (Los Angeles County Clone, LAC) were evaluated by observing the minimum inhibitory concentration.
引用
收藏
页码:602 / 604
页数:3
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