Solubility of naringin in ethanol and water mixtures from 283.15 to 318.15 K

被引：21

作者：

Zhang, Jiye ^{[1
]}

Zhang, Peipei ^{[2
]}

Liu, Tingting ^{[1
]}

Zhou, Li ^{[1
]}

Zhang, Liqin ^{[1
]}

Lin, Rong ^{[2
]}

Yang, Guangde ^{[1
]}

Wang, Weirong ^{[2
]}

Li, Yiping ^{[1
]}

机构：

[1] Xi An Jiao Tong Univ, Hlth Sci Ctr, Sch Pharm, Xian 710061, Peoples R China

[2] Xi An Jiao Tong Univ, Sch Med, Dept Pharmacol, Xian 710061, Peoples R China

来源：

JOURNAL OF MOLECULAR LIQUIDS | 2015年 / 203卷

基金：

中国国家自然科学基金;

关键词：

Naringin; Solubility; Synergistic effect; Enthalpy; Entropy; ACID; SOLVENT; CELLS; MODEL;

D O I：

10.1016/j.molliq.2014.12.039

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The solubility of naringin in the binary system of ethanol and water was measured by using UV spectrophotometric method at the maximum absorption wavelength (UV = 283 nm) from 283.15 K to 318.15 K under atmospheric pressure. The solubility increases with the increasing temperature and in the solvent system it exhibits a synergistic effect. The modified Apelblat model was applied to correlate the experimental solubility data, and the calculated solubilities were in good agreement with the experimental results. The process of the dissolution of naringin was always endothermic, and was influenced by two mechanisms which are enthalpy-driven and entropy-driven. Non-linear enthalpy-entropy compensation was found for naringin in the binary system of ethanol and water. (C) 2014 Elsevier B.V. All rights reserved.

引用

页码：98 / 103

页数：6

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