Anticholinesterase activity of standardized extract of Illicium verum Hook. f. fruits

被引：43
|
作者：
Bhadra, Santanu [1 ]
Mukherjee, Pulok K. [1 ]
Kumar, N. Satheesh [1 ]
Bandyopadhyay, A. [2 ]
机构：
[1] Jadavpur Univ, Dept Pharmaceut Technol, Sch Nat Prod Studies, Kolkata 700032, India
[2] Indian Inst Chem Biol, Kolkata 700032, India
来源：
FITOTERAPIA | 2011年 / 82卷 / 03期
关键词：
Acetylcholinesterase; Butyrylcholinesterase; Anethole; Illicium verum; Alzheimer's disease; ACETYLCHOLINESTERASE INHIBITORY-ACTIVITY; ESSENTIAL OIL; COMPONENTS; PLANTS;
D O I：
10.1016/j.fitote.2010.11.003
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Illicium verum is a well known spice in traditional Indian system for its therapeutic potential. The present study was aimed to evaluate the acetylcholinesterase (AChE) and butyrylcholinesterase inhibitory (BChE) activity of standardized extracts of I. verum and its oil. Present study confirmed that anethole contributed to the anticholinesterase activity of I. verum, with more specificity towards AChE. IC50 for AChE and BChE inhibitory activity of anethole was 39.89 +/- 0.32 mu g/mL and 75.35 +/- 1.47 mu g/ml, whereas for the oil, 36.00 +/- 0.44 mu g/mL and 70.65 +/- 0.96 mu g/mL respectively. Therefore I. verum can be a good lead as anti-cholinesterase agent from natural resources. (c) 2010 Elsevier B.V. All rights reserved.
引用
收藏
页码：342 / 346
页数：5
相关论文
共 50 条
  • [21] Based on CiteSpace Insights into Illicium verum Hook. f. Current Hotspots and Emerging Trends and China Resources Distribution
    He, Zhoujian
    Huan, Jie
    Ye, Meng
    Liang, Dan
    Wu, Yongfei
    Li, Wenjun
    Gong, Xiao
    Jiang, Liqiong
    FOODS, 2024, 13 (10)
  • [22] Star Anise (Illicium verum Hook. f.) as Quorum Sensing and Biofilm Formation Inhibitor on Foodborne Bacteria: Study in Milk
    Rahman, Md Ramim Tanver
    Lou, Zaixiang
    Zhang, Jun
    Yu, Fuhao
    Timilsena, Yakindra Prasad
    Zhang, Caili
    Zhang, Yi
    Bakry, Amr M.
    JOURNAL OF FOOD PROTECTION, 2017, 80 (04) : 645 - 653
  • [23] Rapid separation of shikimic acid from Chinese star anise (Illicium verum Hook. f.) with hot water extraction
    Ohira, Hiroki
    Torii, Naota
    Aida, Taku M.
    Watanabe, Masaru
    Smith, Richard L., Jr.
    SEPARATION AND PURIFICATION TECHNOLOGY, 2009, 69 (01) : 102 - 108
  • [24] Study on Steam Extraction Technology Assisted by Microwave of Anise Star Oil from the Fruit of Illicium verum Hook. f.
    Yang, Guoen
    Wang, Guiwu
    Wu, Zhiping
    Li, Xiangzhou
    ADVANCED MANUFACTURING SYSTEMS, PTS 1-3, 2011, 201-203 : 2935 - 2938
  • [25] Combined NIR/MIR analysis: A novel method for the classification of complex substances such as Illicium verum Hook. F. and its adulterants
    Wang, Yong
    Mei, Minghua
    Ni, Yongnian
    Kokot, Serge
    SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2014, 130 : 539 - 545
  • [26] Microwave extraction of essential oils from dried fruits of Illicium verum Hook. f. and Cuminum cyminum L. using ionic liquid as the microwave absorption medium
    Zhai, Yujuan
    Sun, Shuo
    Wang, Ziming
    Cheng, Jianhua
    Sun, Yantao
    Wang, Lu
    Zhang, Yupu
    Zhang, Hanqi
    Yu, Aimin
    JOURNAL OF SEPARATION SCIENCE, 2009, 32 (20) : 3544 - 3549
  • [27] TECHNOLOGICAL PROSPECTION OF ANTIBACTERIAL AND ANTIFUNGAL POTENTIAL OF STAR ANISE (Illicium verum HOOK F.)
    dos Santos Silva, Rafael Aleixo
    Nunes Calumby, Rodrigo Jose
    da Silva Santos, Iris Karolayne
    Souza da Silva, Sarnia Andricia
    de Almeida, Lara Mendes
    do Nascimento, Ticiano Gomes
    Basilio Junior, Irinaldo Diniz
    HUMANIDADES & INOVACAO, 2020, 7 (04): : 327 - 338
  • [28] A Comprehensive Review of the Pharmacology, Chemistry, Traditional Uses and Quality Control of Star Anise (Illicium verum Hook. F.): An Aromatic Medicinal Plant
    Zou, Qiyuan
    Huang, Yuanyuan
    Zhang, Wenyan
    Lu, Chen
    Yuan, Jingquan
    MOLECULES, 2023, 28 (21):
  • [29] In vitro cytotoxicity, α-glucosidase inhibition, antioxidant, and free radical scavenging activities of Illicium griffithii Hook. f. & Thoms fruits
    Vijayakumar, A.
    Jeyaraj, B.
    Raj, M. Karunai
    Christhudas, I. V. S. Nimal
    Balachandran, C.
    Agastian, P.
    Ignacimuthu, S.
    MEDICINAL CHEMISTRY RESEARCH, 2014, 23 (06) : 2769 - 2779
  • [30] In vitro cytotoxicity, α-glucosidase inhibition, antioxidant, and free radical scavenging activities of Illicium griffithii Hook. f. & Thoms fruits
    A. Vijayakumar
    B. Jeyaraj
    M. Karunai Raj
    I. V. S. Nimal Christhudas
    C. Balachandran
    P. Agastian
    S. Ignacimuthu
    Medicinal Chemistry Research, 2014, 23 : 2769 - 2779
12345