Examination of point mutations within the ABL kinase domain of Bcr-Abl fusion gene in Chinese patients with chronic myeloid leukemia who develop imatinib resistance

被引:0
|
作者
Yang, Dongguang [1 ]
Zhang, Ri [2 ]
Gang, Honglin [3 ]
Gu, Jian [2 ]
Cen, Jian Nong [2 ]
机构
[1] Jiang Su Su Bei People Hosp, Yangzhou Inst Hematol, Jiangsu, Peoples R China
[2] Suzhou Univ, Affiliated Hosp 1, Jiangsu Inst Hematol, Suzhou 215006, Peoples R China
[3] Yangzhou Univ, Dept Pharmacol, Jiangsu, Peoples R China
关键词
D O I
10.1182/blood.V110.11.4573.4573
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
4573
引用
收藏
页码:214B / 215B
页数:2
相关论文
共 50 条
  • [31] Response to Imatinib mesylate in chronic myeloid leukemia patients with variant BCR-ABL fusion transcripts
    Pratibha Sharma
    Lalit Kumar
    Sujata Mohanty
    Vinod Kochupillai
    Annals of Hematology, 2010, 89 : 241 - 247
  • [32] Targeting the kinase activity of the BCR-ABL fusion protein in patients with chronic myeloid leukemia
    Giles, FJ
    Cortes, JE
    Kantarjian, HM
    CURRENT MOLECULAR MEDICINE, 2005, 5 (07) : 615 - 623
  • [33] Analysis of Two Mutations in the BCR-ABL Fusion Gene Relevant for Monitoring Chronic Myeloid Leukemia Patients
    Duca, Andra-Maria
    Dragomir, Mihaela
    Aposteanu, Silvia
    Coriu, Daniel
    Cimponeriu, Danut
    Stoica, Ileana
    BIOINTERFACE RESEARCH IN APPLIED CHEMISTRY, 2023, 13 (03):
  • [34] Presence of a new BCR-ABL kinase domain mutation, C330G in an imatinib naive patient with chronic myeloid leukemia: very low prevalence of BCR-ABL kinase domain mutations in patients with chronic myeloid leukemia from eastern India
    Kuila, Nivedita
    Dash, Nilima
    Sahoo, Devi Prasad
    Pattnayak, Naresh Chandra
    Biswas, Ghanashyam
    Chakraborty, Soumen
    LEUKEMIA & LYMPHOMA, 2009, 50 (04) : 663 - 666
  • [35] Increase of BCR-ABL/ABL Ratio That Corresponds to BCR-ABL Mutation Detection In Chronic Myeloid Leukemia (CML) Patients Treated by Imatinib (IM)
    Tsaur, Grigory
    Popov, Alexander
    Ivanova, Anna
    Yakovleva, Yulia
    Riger, Tatyana
    Plekhanova, Olga
    Ivanets, Yulia
    Shorikov, Egor
    Saveliev, Leonid
    Fechina, Larisa
    FASEB JOURNAL, 2011, 25
  • [36] Specific assessment of BCR-ABL transcript overexpression and imatinib resistance in chronic myeloid leukemia patients
    Bianchini, Michele
    De Brasi, Carlos
    Gargallo, Patricia
    Gonzalez, Mariana
    Bengio, Raquel
    Larripa, Irene
    EUROPEAN JOURNAL OF HAEMATOLOGY, 2009, 82 (04) : 292 - 300
  • [37] Prevalence and Dynamics of BCR-ABL Independent Gene Mutations in Patients with Chronic Myeloid Leukemia
    Ernst, Thomas
    Rinke, Jenny
    Busch, Melinda
    Ernst, Jana
    Obstfelder, Ellen
    Schmidt, Mathias
    Schafer, Vivien
    Waldau, Anja
    Winkelmann, Nils
    Gruhn, Bernd
    Hochhaus, Andreas
    BLOOD, 2016, 128 (22)
  • [38] Use of direct sequencing for detection of mutations in the BCR-ABL kinase domain in Slovak patients with chronic myeloid leukemia
    Strhakova, L.
    Bujalkova, M. Gerykova
    Hojsikova, I.
    Lukackova, R.
    Behulova, R.
    Mistrik, M.
    Repiska, V.
    NEOPLASMA, 2011, 58 (06) : 548 - 553
  • [39] Lack of Bcr-Abl point mutations in chronic myeloid leukemia patients in chronic phase before imatinib treatment is not predictive of response
    Agirre, X
    Fontalba, A
    Andreu, EJ
    Odero, MD
    Larróyoz, MJ
    Montiel, C
    Calasanz, M
    Fernández-Luna, JL
    Prósper, F
    HAEMATOLOGICA, 2003, 88 (12) : 1425 - 1426
  • [40] Spectrum of BCR-ABL kinase domain mutations in patients with chronic myeloid leukemia from India with suspected resistance to imatinib-mutations are rare and have different distributions
    Markose, Preetha
    Chendamarai, Ezhilarasi
    Balasubramanian, Poonkuzhali
    Velayudhan, Shaji Ramachandran
    Srivastava, Vivi M.
    Mathews, Vikram
    George, Biju
    Viswabandya, Auro
    Srivastava, Alok
    Chandy, Mammen
    LEUKEMIA & LYMPHOMA, 2009, 50 (12) : 2092 - 2095