Loss of claudin-4 reduces DNA damage repair and increases sensitivity to PARP inhibitors

被引:0
|
作者
Yamamoto, Tomomi [1 ]
Webb, Patricia [1 ]
Woodruff, Elizabeth [1 ]
Guntupalli, Saketh [1 ]
Neville, Margaret [2 ]
Behbakht, Kian [1 ]
Bitler, Benjamin [1 ]
机构
[1] Univ Colorado, Aurora, CO USA
[2] Univ Colorado, Sch Med, Aurora, CO USA
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
228
引用
收藏
页码:S126 / S127
页数:2
相关论文
共 50 条
  • [21] LKB1 is a DNA damage response protein that regulates cellular sensitivity to PARP inhibitors
    Wang, Yi-Shu
    Chen, Jianfeng
    Cui, Fengmei
    Wang, Huibo
    Wang, Shuai
    Hang, Wei
    Zeng, Qinghua
    Quan, Cheng-Shi
    Zhai, Ying-Xian
    Wang, Jian-Wei
    Shen, Xiang-Feng
    Jian, Yong-Ping
    Zhao, Rui-Xun
    Werle, Kaitlin D.
    Cui, Rutao
    Liang, Jiyong
    Li, Yu-Lin
    Xu, Zhi-Xiang
    ONCOTARGET, 2016, 7 (45) : 73389 - 73401
  • [22] ATM loss in NSCLC increases sensitivity to cisplatin and PARP inhibition
    Bebb, D. G.
    Petersen, L. F.
    Moore, J.
    Elegbede, A.
    Lees-Miller, S.
    ANNALS OF ONCOLOGY, 2019, 30
  • [23] TARGETED INHIBITION OF HSP90 IMPAIRS DNA-DAMAGE RESPONSE PROTEINS AND INCREASES THE SENSITIVITY OF OVARIAN CARCINOMA CELLS TO PARP INHIBITORS
    Gabbasov, Rashid
    Benrubi, I. Daniel
    O'Brien, Shane W.
    Krais, John J.
    Johnson, Neil
    Litwin, Samuel
    Connolly, Denise C.
    CLINICAL CANCER RESEARCH, 2019, 25 (22) : 206 - 206
  • [24] Claudin-4 interacts with the small GTPase Rap1 and accelerates epithelial repair
    Sutherland, Katherine Marie
    Bentley, Trevor
    LaFemina, Michael
    Ho, Gwen
    Hirsch, Jan
    Frank, James
    FASEB JOURNAL, 2012, 26
  • [25] Correction: GLI1 confers resistance to PARP inhibitors by activating the DNA damage repair pathway
    Ikeuchi, Hiroshi
    Matsuno, Yusuke
    Kusumoto-Matsuo, Rika
    Kojima, Shinya
    Ueno, Toshihide
    Ikegami, Masachika
    Kitada, Rina
    Sumiyoshi-Okuma, Hitomi
    Kojima, Yuki
    Yonemori, Kan
    Yatabe, Yasushi
    Takamochi, Kazuya
    Suzuki, Kenji
    Yoshioka, Ken-ichi
    Mano, Hiroyuki
    Kohsaka, Shinji
    ONCOGENE, 2024, 43 (41) : 3079 - 3079
  • [26] Analogs of the novel phytohormone, strigolactone, trigger apoptosis and synergize with PARP inhibitors by inducing DNA damage and inhibiting DNA repair
    Croglio, Michael P.
    Haake, Jefferson M.
    Ryan, Colin P.
    Wang, Victor S.
    Lapier, Jennifer
    Schlarbaum, Jamie P.
    Dayani, Yaron
    Artuso, Emma
    Prandi, Cristina
    Koltai, Hinanit
    Agama, Keli
    Pommier, Yves
    Chen, Yu
    Tricoli, Lucas
    LaRocque, Jeannine R.
    Albanese, Christopher
    Yarden, Ronit I.
    ONCOTARGET, 2016, 7 (12) : 13984 - 14001
  • [27] New Insights into PARP Inhibitors' Effect on Cell Cycle and Homology-Directed DNA Damage Repair
    Jelinic, Petar
    Levine, Douglas A.
    MOLECULAR CANCER THERAPEUTICS, 2014, 13 (06) : 1645 - 1654
  • [28] DNA-methylation-dependent alterations of claudin-4 expression in human bladder carcinoma
    Boireau, Stephanie
    Buchert, Michael
    Samuel, Michael S.
    Pannequin, Julie
    Ryan, Joanne L.
    Choquet, Armelle
    Chapuis, Heliette
    Rebillard, Xavier
    Avances, Christophe
    Ernst, Matthias
    Joubert, Dominique
    Mottet, Nicolas
    Hollande, Frederic
    CARCINOGENESIS, 2007, 28 (02) : 246 - 258
  • [29] TRIM33 loss in Multiple Myeloma is associated with defective DNA repair and sensitivity to PARP inhibition
    McAvera, Roisin
    Morgan, Jonathan
    Mills, Ken
    Crawford, Lisa
    CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2021, 21 : S68 - S68
  • [30] Adrenomedullin alleviates mucosal injury in experimental colitis and increases claudin-4 expression in the colonic epithelium
    Kawaguchi, Makiko
    Kataoka, Hiroaki
    Kiwaki, Takumi
    Weiting, Liang
    Nagata, Sayaka
    Kitamura, Kazuo
    Fukushima, Tsuyoshi
    FEBS OPEN BIO, 2023, 13 (04): : 713 - 723