A MULTIPLE-ONCE DAILY DOSE, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY OF THE PHARMACOKINETICS AND TOLERABILITY OF ABT-089, A NOVEL NEURONAL NICOTINIC RECEPTOR PARTIAL AGONIST, IN HEALTHY VOLUNTEERS

被引:0
|
作者
Garimella, Tushar [1 ]
Awni, Walid [1 ]
Yan, Jun [1 ]
Florian, Hana [1 ]
Dutta, Sandeep [1 ]
机构
[1] Abbott, Global Pharmaceut Res & Dev, Abbott Pk, IL USA
来源
JOURNAL OF CLINICAL PHARMACOLOGY | 2010年 / 50卷 / 09期
关键词
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
51
引用
收藏
页码:1068 / 1068
页数:1
相关论文
共 50 条
  • [31] A First-In-Human, Randomised, Double-Blind, Placebo-Controlled Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Oral Ketamine in Healthy Volunteers
    Silman, Daniel
    Gadelrab, Romayne
    Qureshi, Mutahira
    Stein, Hans
    Mehta, Mitul
    Carmelline, Pietro
    Young, Allan
    Reilly, Carmel
    Duncan, Graeme
    Juruena, Mario
    NEUROPSYCHOPHARMACOLOGY, 2024, 49 : 155 - 155
  • [32] A phase I double-blind, placebo-controlled, single rising dose study to determine the safety, tolerability, and pharmacokinetics of oral YM934 in healthy male volunteers
    Burggraaf, J
    Schoemaker, RC
    Terpstra, IJ
    Cohen, AF
    JOURNAL OF CLINICAL PHARMACOLOGY, 1998, 38 (01): : 45 - 53
  • [33] Safety, Tolerability, Pharmacokinetics, and Pharmacodynamic Properties of the GPR40 Agonist TAK-875: Results From a Double-Blind, Placebo-Controlled Single Oral Dose Rising Study in Healthy Volunteers
    Naik, Himanshu
    Vakilynejad, Majid
    Wu, Jingtao
    Viswanathan, Prabhakar
    Dote, Nobuhito
    Higuchi, Tomoaki
    Leifke, Eckhard
    JOURNAL OF CLINICAL PHARMACOLOGY, 2012, 52 (07): : 1007 - 1016
  • [34] Safety, Tolerability, and Pharmacokinetics of Therapeutic and Supratherapeutic Doses of Tramadol Hydrochloride in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Multiple-Ascending-Dose Study
    DeLemos, Byron
    Richards, Henry M.
    Vandenbossche, Joris
    Ariyawansa, Jay
    Natarajan, Jaya
    Alexander, Binu
    Ramakrishna, Tage
    Murtaugh, Thomas
    Stahlberg, Hans-Juergen
    CLINICAL PHARMACOLOGY IN DRUG DEVELOPMENT, 2017, 6 (06): : 592 - 603
  • [35] Randomized, double-blind, placebo-controlled, multiple-dose study of the safety, tolerability and pharmacokinetics of benvitimod, a candidate drug for the treatment of psoriasis
    Zhao, L.
    Chen, X.
    Cai, L.
    Zhang, C.
    Wang, Q.
    Jing, S.
    Chen, G.
    Li, J.
    Zhang, J.
    Fang, Y.
    JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, 2014, 39 (04) : 418 - 423
  • [36] Dasiglucagon Effects on QTc in Healthy Volunteers: A Randomized, Placebo-Controlled, Dose-Escalation, Double-Blind Study
    Tehranchi, Ramin
    Pettersson, Jonas
    Melgaard, Anita E.
    Seitz, Friedeborg
    Valeur, Anders
    Maarbjerg, Stine Just
    CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL, 2022, 96
  • [37] Pharmacokinetics, Safety, and Tolerability of Single- and Multiple-Dose Once-Daily Baricitinib in Healthy Chinese Subjects: A Randomized Placebo-Controlled Study
    Zhao, Xia
    Sheng, Xiao Yan
    Payne, Christopher D.
    Zhang, Xin
    Wang, Feng
    Cui, Yi Min
    CLINICAL PHARMACOLOGY IN DRUG DEVELOPMENT, 2020, 9 (08): : 952 - 960
  • [38] Pranidipine, a novel calcium antagonist, once daily, for the treatment of hypertension: A multicenter, double-blind, placebo-controlled dose-finding study
    Rosenthal, J
    Hittel, N
    Stumpe, KO
    CARDIOVASCULAR DRUGS AND THERAPY, 1996, 10 (01) : 59 - 66
  • [39] Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Alirocumab in Healthy Chinese Subjects: A Randomized, Double-Blind, Placebo-Controlled, Ascending Single-Dose Study
    Haiyan Li
    Yudong Wei
    Zhenhua Yang
    Shuang Zhang
    Xiuxiu Xu
    Mengmeng Shuai
    Olivier Vitse
    Yiwen Wu
    Marie T. Baccara-Dinet
    Yi Zhang
    Jianyong Li
    American Journal of Cardiovascular Drugs, 2020, 20 : 489 - 503
  • [40] Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Alirocumab in Healthy Chinese Subjects: A Randomized, Double-Blind, Placebo-Controlled, Ascending Single-Dose Study
    Li, Haiyan
    Wei, Yudong
    Yang, Zhenhua
    Zhang, Shuang
    Xu, Xiuxiu
    Shuai, Mengmeng
    Vitse, Olivier
    Wu, Yiwen
    Baccara-Dinet, Marie T.
    Zhang, Yi
    Li, Jianyong
    AMERICAN JOURNAL OF CARDIOVASCULAR DRUGS, 2020, 20 (05) : 489 - 503