Polymeric Microneedles' Swelling Property Characterizations using Micro-Optical Coherence Tomography

被引：0
|
作者：
Yu, Xiaojun [1 ,2 ]
Seeni, Razina Z. [3 ]
Liu, Linbo [2 ]
Xu, Chenjie [3 ]
机构：
[1] Northwest Polytech Univ, Sch Automat, Xian 710072, Shaanxi, Peoples R China
[2] Nanyang Technol Univ, Sch Elect & Elect Engn, Singapore 639798, Singapore
[3] Nanyang Technol Univ, Sch Chem & Biomed Engn, Singapore 637459, Singapore
来源：
2017 CONFERENCE ON LASERS AND ELECTRO-OPTICS PACIFIC RIM (CLEO-PR) | 2017年
关键词：
Microneedles; iron oxide nanoparticles; contrast agent; OCT; swelling imaging; DRUG-DELIVERY;
D O I：
暂无
中图分类号：
TM [电工技术]; TN [电子技术、通信技术];
学科分类号：
0808 ; 0809 ;
摘要：
We report on noninvasive characterization of MNs' real-time swelling property in mice-skin using a lab-built micro-optical coherence tomography (mu OCT). Specifically, we propose to encapsulate the iron-oxide (Fe3O4) nanoparticles into polymeric MNs as contrast agent to enhance OCT image contrast, and then evaluate its influences on contrast enhancement quantitatively. The MNs' real-time temporal swelling behaviors in mice-skin are recorded and analyzed. This is the first quantitative study on MNs' temporal swelling property in biological tissue using mu OCT.
引用
收藏
页数：2
相关论文
共 50 条
  • [1] Iron Oxide Nanoparticle-Powered Micro-Optical Coherence Tomography for in Situ Imaging the Penetration and Swelling of Polymeric Microneedles in the Skin
    Seeni, Razina Z.
    Yu, Xiaojun
    Chang, Hao
    Chen, Peng
    Liu, Linbo
    Xu, Chenjie
    [J]. ACS APPLIED MATERIALS & INTERFACES, 2017, 9 (24) : 20340 - 20347
  • [2] Micro-optical coherence tomography of the mammalian cochlea
    Iyer, Janani S.
    Batts, Shelley A.
    Chu, Kengyeh K.
    Sahin, Mehmet I.
    Leung, Hui Min
    Tearney, Guillermo J.
    Stankovic, Konstantina M.
    [J]. SCIENTIFIC REPORTS, 2016, 6
  • [3] Micro-optical coherence tomography of the mammalian cochlea
    Janani S. Iyer
    Shelley A. Batts
    Kengyeh K. Chu
    Mehmet I. Sahin
    Hui Min Leung
    Guillermo J. Tearney
    Konstantina M. Stankovic
    [J]. Scientific Reports, 6
  • [4] MICRO-OPTICAL SWELLING
    DAVISON, S
    [J]. RUBBER AGE, 1968, 100 (11): : 76 - &
  • [5] Endomicroscopy of the human cochlea using a micro-optical coherence tomography catheter
    Iyer, Janani S.
    Yin, Biwei
    Stankovic, Konstantina M.
    Tearney, Guillermo J.
    [J]. SCIENTIFIC REPORTS, 2021, 11 (01)
  • [6] Reliable Internal Fingerprint Detection using Micro-Optical Coherence Tomography
    Yu, Xiaojun
    Xiong, Qiaozhou
    Luo, Yuemei
    Wang, Nanshuo
    Wang, Lulu
    Tey, Hong Liang
    Liu, Linbo
    [J]. 2017 CONFERENCE ON LASERS AND ELECTRO-OPTICS PACIFIC RIM (CLEO-PR), 2017,
  • [7] Stromal Nerve Imaging and Tracking Using Micro-Optical Coherence Tomography
    Elhardt, Carolin
    Wertheimer, Christian M.
    Wartak, Andreas
    Zhao, Jie
    Leung, Hui Min
    Kassumeh, Stefan A.
    Yin, Biwei
    Tearney, Guillermo J.
    Birngruber, Reginald
    [J]. TRANSLATIONAL VISION SCIENCE & TECHNOLOGY, 2020, 9 (05):
  • [8] Particle-Tracking Microrheology Using Micro-Optical Coherence Tomography
    Chu, Kengyeh K.
    Mojahed, Diana
    Fernandez, Courtney M.
    Li, Yao
    Liu, Linbo
    Wilsterman, Eric J.
    Diephuis, Bradford
    Birket, Susan E.
    Bowers, Hannah
    Solomon, G. Martin
    Schuster, Benjamin S.
    Hanes, Justin
    Rowe, Steven M.
    Tearney, Guillermo J.
    [J]. BIOPHYSICAL JOURNAL, 2016, 111 (05) : 1053 - 1063
  • [9] Endomicroscopy of the human cochlea using a micro-optical coherence tomography catheter
    Janani S. Iyer
    Biwei Yin
    Konstantina M. Stankovic
    Guillermo J. Tearney
    [J]. Scientific Reports, 11
  • [10] RHEOLOGICAL VALIDATION OF PARTICLETRACKING MICRO-OPTICAL COHERENCE TOMOGRAPHY
    Wilsterman, E.
    Chu, K. K.
    Li, Y.
    Diephuis, B.
    Birket, S.
    Schuster, B. S.
    Hanes, J.
    Rowe, S. M.
    Tearney, G. J.
    [J]. PEDIATRIC PULMONOLOGY, 2013, 48 : 301 - 302
12345