DEVELOPMENT OF GRANULATION TECHNOLOGY FOR LIPOPHILIC EXTRACTS

被引：0
|
作者：
Minina, S. A. [1 ]
Ozhigova, M. G. [1 ]
机构：
[1] St Petersburg State Chemicopharmaceut Acad, St Petersburg, Russia
来源：
PHARMACEUTICAL CHEMISTRY JOURNAL | 2010年 / 44卷 / 04期
关键词：
granulation technology; lipophilic substances; surfactants;
D O I：
10.1007/s11094-010-0434-5
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
A new method for the granulation of lipophilic substances is described using as examples an extract from the bark of Pygeum africanum (Hook. f. Kalkman) and polyextracts from leaves of Urtica dioica L. The proposed method is based on a combined process of melting and dispersion in aqueous solutions of surfactants followed by the use of the resulting dispersed solution as a binding agent for granulation. This technology is recommended for the production of solid dosage forms of drugs containing lipophilic substances.
引用
收藏
页码：213 / 215
页数：3
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