Inhibition-reduction theory (L. Hasher & R. Zacks, 1988) hypothesizes that the age-related decline in working memory (WM) span is a result of a decrease in the ability to inhibit irrelevant information in WM. Using the Rasch psychometric model, this study found that later trials on 2 WM span tasks were more difficult for older adults than for younger adults, consistent with inhibition-reduction theory's hypothesis that older adults are more susceptible to the effects of proactive interference (PI). Furthermore, after accounting for differential susceptibility to the effects of PI, age-related variance in WM span was reduced by about half. These results suggest that differential susceptibility to PI may account for a substantial portion, although not all, of the age-related decline in WM span.
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Yale Univ, Sch Med, Dept Neurobiol, New Haven, CT 06510 USAYale Univ, Sch Med, Dept Neurobiol, New Haven, CT 06510 USA
Wang, Min
Gamo, Nao J.
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Yale Univ, Sch Med, Dept Neurobiol, New Haven, CT 06510 USAYale Univ, Sch Med, Dept Neurobiol, New Haven, CT 06510 USA
Gamo, Nao J.
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Yang, Yang
Jin, Lu E.
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Yale Univ, Sch Med, Dept Neurobiol, New Haven, CT 06510 USAYale Univ, Sch Med, Dept Neurobiol, New Haven, CT 06510 USA
Jin, Lu E.
Wang, Xiao-Jing
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Yale Univ, Sch Med, Dept Neurobiol, New Haven, CT 06510 USAYale Univ, Sch Med, Dept Neurobiol, New Haven, CT 06510 USA
Wang, Xiao-Jing
Laubach, Mark
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Yale Univ, Sch Med, Dept Neurobiol, New Haven, CT 06510 USA
John B Pierce Lab, New Haven, CT 06510 USAYale Univ, Sch Med, Dept Neurobiol, New Haven, CT 06510 USA
Laubach, Mark
Mazer, James A.
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Yale Univ, Sch Med, Dept Neurobiol, New Haven, CT 06510 USAYale Univ, Sch Med, Dept Neurobiol, New Haven, CT 06510 USA
Mazer, James A.
Lee, Daeyeol
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Yale Univ, Sch Med, Dept Neurobiol, New Haven, CT 06510 USAYale Univ, Sch Med, Dept Neurobiol, New Haven, CT 06510 USA
Lee, Daeyeol
Arnsten, Amy F. T.
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Yale Univ, Sch Med, Dept Neurobiol, New Haven, CT 06510 USAYale Univ, Sch Med, Dept Neurobiol, New Haven, CT 06510 USA