New nitric oxide (NO)-releasing statin derivatives with enhanced anti-inflammatory properties

被引：0
|
作者：
Bonazzi, A [1 ]
Guzzetta, M [1 ]
Ferrario, M [1 ]
Ongini, E [1 ]
Monopoli, A [1 ]
Del Soldato, P [1 ]
机构：
[1] Nicox Res Inst, Milan, Italy
来源：
CIRCULATION | 2003年 / 108卷 / 17期
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
184
引用
收藏
页码：39 / 39
页数：1
相关论文
共 50 条
  • [21] Anti-Inflammatory and Anti-Atherogenic Activities of Ncx 6560, a Nitric Oxide (no)-Donating Statin, in Hypercholesterolemic Mice
    Momi, Stefania
    Emanuela, Falcinelli
    Paolo, Alberti F.
    Angela, Monopoli
    Daniela, Miglietta
    Ongini, Ennio
    Gresele, Paolo
    CIRCULATION, 2010, 122 (21)
  • [22] Synthesis and evaluation of anti-inflammatory, analgesic, ulcerogenicity and nitric oxide-releasing studies of novel ibuprofen analogs as nonulcerogenic derivatives
    Aniket P. Sarkate
    Deepak K. Lokwani
    Ajit A. Patil
    Shashikant V. Bhandari
    Kailash G. Bothara
    Medicinal Chemistry Research, 2011, 20 : 795 - 808
  • [23] Synthesis and evaluation of anti-inflammatory, analgesic, ulcerogenicity and nitric oxide-releasing studies of novel ibuprofen analogs as nonulcerogenic derivatives
    Sarkate, Aniket P.
    Lokwani, Deepak K.
    Patil, Ajit A.
    Bhandari, Shashikant V.
    Bothara, Kailash G.
    MEDICINAL CHEMISTRY RESEARCH, 2011, 20 (07) : 795 - 808
  • [24] Gastrointestinal-sparing anti-inflammatory drugs: The development of nitric oxide-releasing NSAIDs
    Wallace, JL
    Elliott, SN
    Del Soldato, P
    McKnight, W
    Sannicolo, F
    Cirino, G
    DRUG DEVELOPMENT RESEARCH, 1997, 42 (3-4) : 144 - 149
  • [25] NOSH compounds: Nitric oxide- and hydrogen sulfide-releasing hybrids, a new class of anti-inflammatory pharmaceuticals
    Vannini, Federica
    Kim, Han-Bee
    Chattopadhyay, Mitali
    Kodela, Ravinder
    Kashfi, Khosrow
    CANCER RESEARCH, 2012, 72
  • [26] A new nitric oxide steroid derivative (NCX-1015) with enhanced anti-inflammatory properties reduces colonic inflammation in mice.
    Stefano, F
    Luca, S
    Elisabetta, A
    Eleonora, D
    Piero, DS
    Antonio, M
    GASTROENTEROLOGY, 2000, 118 (04) : A587 - A587
  • [27] Design and synthesis of furoxan-based nitric oxide-releasing glucocorticoid derivatives with potent anti-inflammatory activity and improved safety
    Fang, Lei
    Zhang, Yihua
    Lehmann, Jochen
    Wang, You
    Ji, Hui
    Ding, Dayong
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2007, 17 (04) : 1062 - 1066
  • [28] Effects of nitric oxide releasing non-steroidal anti-inflammatory drug derivatives on secretory activity in rat gastric epithelial cells
    Lodge, CS
    Moran, AE
    Hodder, SJ
    Hanson, PJ
    Brown, JF
    BRITISH JOURNAL OF PHARMACOLOGY, 2000, 129 : U94 - U94
  • [29] Ibuprofen-arginine generates nitric oxide and has enhanced anti-inflammatory effects
    De Palma, Clara
    Di Paola, Rosanna
    Perrotta, Cristiana
    Mazzon, Emanuela
    Cattaneo, Dario
    Trabucchi, Emilio
    Cuzzocrea, Salvatore
    Clementi, Emilio
    PHARMACOLOGICAL RESEARCH, 2009, 60 (04) : 221 - 228
  • [30] Nitric oxide regulates immune cell bioenergetic: A mechanism to understand immunomodulatory functions of nitric oxide-releasing anti-inflammatory drugs
    Fiorucci, S
    Mencarelli, A
    Distrutti, E
    Baldoni, M
    del Soldato, P
    Morelli, A
    JOURNAL OF IMMUNOLOGY, 2004, 173 (02): : 874 - 882
12345