Necrotizing toxoplasmic encephalitis in a child with the X-linked hyper-IgM syndrome

被引：19

作者：

Tsuge, I ^{[1
]}

Matsuoka, H ^{[1
]}

Nakagawa, A ^{[1
]}

Kamachi, Y ^{[1
]}

Aso, K ^{[1
]}

Negoro, T ^{[1
]}

Ito, M ^{[1
]}

Torii, S ^{[1
]}

Watanabe, K ^{[1
]}

机构：

[1] Nagoya Univ Hosp, Dept Pathol, Nagoya, Aichi 466, Japan

来源：

EUROPEAN JOURNAL OF PEDIATRICS | 1998年 / 157卷 / 09期

关键词：

hyper-IgM syndrome; CD40; ligand; necrotizing toxoplasmic encephalitis;

D O I：

10.1007/s004310050925

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

We report on a 9-year-old boy with the hyper-IgM syndrome who presented with rapid impairment of consciousness. The brain CT scan showed multiple round lucencies, and the brain histology revealed necrotizing toxoplasmic encephalitis. This patient, whose CD40/CD40 ligand system was impaired, indicates the importance of this system for defence against toxoplasmic infection. Conclusion Although disseminated toxoplasmosis is a rare complication of the hyper-IgM syndrome, it must be included in the differential diagnosis of infections.

引用

页码：735 / 737

页数：3

共 50 条

[41] X-linked Hyper-IgM Syndrome: A Phenotype of Crohn's Disease with Hemophagocytic Lymphohistiocytosis
Qiu, Kun-yin
Liao, Xiong-yu
Wu, Ruo-hao
Huang, Ke
Fang, Jian-pei
Zhou, Dun-hua
PEDIATRIC HEMATOLOGY AND ONCOLOGY, 2017, 34 (08) : 428 - 434
[42] CD40 LIGAND AND ITS ROLE IN X-LINKED HYPER-IGM SYNDROME
CALLARD, RE
ARMITAGE, RJ
FANSLOW, WC
SPRIGGS, MK
IMMUNOLOGY TODAY, 1993, 14 (11): : 559 - 564
[43] X-linked hyper-IgM syndrome associated with a rapid course of progressive multifocal leukoencephalopathy
Illes, Z.
Aschermann, Z.
Gomori, E.
Kovacs, G. G.
Simon, G.
Pal, E.
Komoly, S.
Marodi, L.
JOURNAL OF NEURAL TRANSMISSION, 2007, 114 (07) : CXXXI - CXXXI
[44] A new mutation affecting the tnfh domain in a patient with X-linked hyper-igm syndrome
Cunha, J. M.
Vasconcelos, D. M.
Oliveira, J. B.
Santos, A. R.
Wakim, V. L.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 2008, 154 : 179 - 180
[45] Invasive Adenocarcinoma of Large Intestine and Gallbladder in a Patient with X-Linked Hyper-IgM Syndrome
Tantou, S.
Stylianidis, G.
Argyrakos, T.
Tzanoudaki, M.
Makatsoris, T.
Liatsis, M.
Kanariou, M.
JOURNAL OF CLINICAL IMMUNOLOGY, 2014, 34 : S472 - S473
[46] Defective antigen-induced lymphocyte proliferation in the X-linked hyper-IgM syndrome
Ameratunga, R
Lederman, HM
Sullivan, KE
Ochs, HD
Seyama, K
French, JK
Prestidge, R
Marbrook, J
Fanslow, WC
Winkelstein, JA
JOURNAL OF PEDIATRICS, 1997, 131 (01): : 147 - 150
[47] Cutaneous sarcoid-like granulomas in a patient with X-linked hyper-IgM syndrome
Gallerani, I
Innocenti, DD
Coronella, G
Berti, S
Amato, L
Moretti, S
Fabbri, P
PEDIATRIC DERMATOLOGY, 2004, 21 (01) : 39 - 43
[48] Autoimmune retinopathy with RPE hypersensitivity and 'negative ERG' in X-linked hyper-IgM syndrome
Schuster, A
Apfelstedt-Sylla, E
Pusch, CM
Zrenner, E
Thirkill, CE
OCULAR IMMUNOLOGY AND INFLAMMATION, 2005, 13 (2-3) : 235 - 243
[49] Patient Specific Targeted Gene Therapy In The Treatment Of X-Linked Hyper-IgM Syndrome
Kuo, Caroline Y.
Joglekar, Alok
Kohn, Donald B.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2014, 133 (02) : AB162 - AB162
[50] ACQUIRED HYPER-IGM SYNDROME WITH NECROTIZING GRANULOMA
GOLDSTEIN, MF
KORNSTEIN, MJ
TALBOT, S
LEVINSON, AI
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1985, 75 (04) : 472 - 478

← 1 2 3 4 5 →