Mechanical unfolding and refolding of proteins: An off-lattice model study

被引：0

作者：

Li, FY ^{[1
]}

Yuan, JM

Mou, CY

机构：

[1] Natl Taiwan Univ, Dept Chem, Taipei 106, Taiwan

[2] Drexel Univ, Dept Phys, Philadelphia, PA 19104 USA

来源：

PHYSICAL REVIEW E | 2001年 / 63卷 / 02期

关键词：

D O I：

暂无

中图分类号：

O35 [流体力学]; O53 [等离子体物理学];

学科分类号：

070204 ; 080103 ; 080704 ;

摘要：

Using an off-lattice model, we investigate the response of a protein molecule to external stretching and release. In particular we study the passive force in a protein as a function of the extension of the protein. These force-extension curves exhibit hysteresis loops, whose areas increase with the pulling rate and decrease with thermal noise. Most of these results seem to be appropriately described by a cusp catastrophe.

引用

页数：10

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