Mechanical unfolding and refolding of proteins: An off-lattice model study

被引：0
|
作者：
Li, FY [1 ]
Yuan, JM
Mou, CY
机构：
[1] Natl Taiwan Univ, Dept Chem, Taipei 106, Taiwan
[2] Drexel Univ, Dept Phys, Philadelphia, PA 19104 USA
来源：
PHYSICAL REVIEW E | 2001年 / 63卷 / 02期
关键词：
D O I：
暂无
中图分类号：
O35 [流体力学]; O53 [等离子体物理学];
学科分类号：
070204 ; 080103 ; 080704 ;
摘要：
Using an off-lattice model, we investigate the response of a protein molecule to external stretching and release. In particular we study the passive force in a protein as a function of the extension of the protein. These force-extension curves exhibit hysteresis loops, whose areas increase with the pulling rate and decrease with thermal noise. Most of these results seem to be appropriately described by a cusp catastrophe.
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页数：10
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