Development of functional Haemophilus Influenzae type b antibodies after vaccination of autologous stem cell transplant recipients

被引:0
|
作者
van der Velden, Ankie M. T. [1 ,3 ]
Claessen, Anke M. E. [2 ]
van Velzen-Blad, Heleen [2 ]
Biesma, Douwe H. [1 ]
Rijkers, Ger T. [3 ]
机构
[1] Sint Antonius Hosp Nieuwegein, Dept Internal Med, Nieuwegein, Netherlands
[2] Sint Antonius Hosp Nieuwegein, Dept Med Microbiol & Immunol, Nieuwegein, Netherlands
[3] Univ Med Ctr Utrecht, Univ Childrens Hosp Wilhelmina Kinderziekenhuis, Dept Immunol, Lab Paediat Immunol, Utrecht, Netherlands
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中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Sixteen autologous stem cell transplant recipients received three vaccinations with conjugated haemophilus influenzae type b vaccine. Quantitative and qualitative aspects of the antibody response were studied. The vaccination schedule resulted in high antibody response rates and functional maturation of antibodies, as measured by antibody avidity and phagocytosis-inducing capacity.
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页码:1582 / 1584
页数:3
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