A Novel 1-Glycosyl-1H-triazole-Based P,N Ligand for Rhodium-Catalyzed Asymmetric Hydrosilylation of Ketones

被引：10
|
作者：
Shen, Chao [1 ,2 ]
Zhang, Peng-Fei [1 ]
Chen, Xin-Zhi [2 ]
机构：
[1] Hangzhou Normal Univ, Coll Mat Chem & Chem Engn, Hangzhou 310036, Zhejiang, Peoples R China
[2] Zhejiang Univ, Coll Mat Chem & Chem Engn, Hangzhou 310027, Peoples R China
来源：
HELVETICA CHIMICA ACTA | 2010年 / 93卷 / 12期
关键词：
ENANTIOSELECTIVE HYDROSILYLATION; CLICK CHEMISTRY; METAL-COMPLEXES; CHIRAL LIGANDS; HYDROGENATION;
D O I：
10.1002/hlca.201000093
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A novel class of chiral glycosyl-triazole-based P,N ligands were synthesized by 'click chemistry' and were applied to the Rh-catalyzed asymmetric hydrosilylation of a range of substituted acetophenones. Enantioselective hydrosilylation of acetophenone gave (S)-1-phenylethanol in moderate enantioselectivity (72% ee) and in good conversion (93%).
引用
收藏
页码：2433 / 2438
页数：6
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