Mapping quantitative trait loci (QTL) in autotetraploid species represents a timely and challenging task. Two papers published by Wu and his colleagues proposed statistical methods for QTL mapping in these evolutionarily and economically important species. In this Letter to the Editor, we present critical comments on the fundamental conceptual errors involved, from both statistical and genetic points of view.
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Univ Alabama, Dept Math, Tuscaloosa, AL 35487 USA
Univ Washington, Dept Biostat, Seattle, WA 98195 USAUniv Alabama, Dept Math, Tuscaloosa, AL 35487 USA
Laurie, Cecelia
Wang, Shengchu
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N Carolina State Univ, Dept Stat, Bioinformat Res Ctr, Raleigh, NC 27695 USAUniv Alabama, Dept Math, Tuscaloosa, AL 35487 USA
Wang, Shengchu
Carlini-Garcia, Luciana Aparecida
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Inst Agron Campinas, Ctr Graos & Fibras, Campinas, SP, Brazil
APTA Reg, Polo Ctr Sul, Piracicaba, SP, BrazilUniv Alabama, Dept Math, Tuscaloosa, AL 35487 USA
Carlini-Garcia, Luciana Aparecida
Zeng, Zhao-Bang
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N Carolina State Univ, Dept Stat, Bioinformat Res Ctr, Raleigh, NC 27695 USA
N Carolina State Univ, Dept Biol Sci, Raleigh, NC 27695 USAUniv Alabama, Dept Math, Tuscaloosa, AL 35487 USA