Two- and three-dimensional high-resolution imaging of the human oviduct with optical coherence tomography

Objective: To evaluate the feasibility of optical coherence tomography, a new method of micron-scale imaging, for high-resolution assessment of the oviduct Optical coherence tomography is analogous to ultrasound except that it measures the backreflection of infrared light rather than acoustical waves. Design: The ampulla of a human fallopian tube was imaged in vitro using optical coherence tomography. Images were generated in 2 and 3 dimensions. Setting: University. Patient(s): Samples were obtained from women who had undergone hysterectomy for leiomyomatosis. Intervention(s): None Main Outcome Measure(s): The ability to perform imaging on a micron scale, which is a level of resolution higher than that of any currently available clinical technology. Result(s): Two- and three-dimensional data sets of the reflectance of a human fallopian tube were acquired. A volume of 5 x 5 x 2.5 mm (length x width x depth) was scanned. The axial resolution was 11 mu m, and the lateral resolution at the focus was 20 mu m. The data sets shelved detailed structures of the fallopian tube. Conclusion(s): Our ability to obtain micron-scale two- and three-dimensional images of an in vitro oviduct suggests that it may be possible to identify and surgically treat tubal causes of infertility. (Fertil Steril(R) 1998;70:155-8. (C) 1998 by American Society for Reproductive Medicine.).