Malignant peripheral nerve sheath tumor in dogs: three cases report

Anatomo-clinical and immunohistochemical findings on three dogs with peripheral nerve sheath tumors assisted at the veterinary hospital are described. Animals showed different clinical signs depending on the location of the tumor. According to microscopy, neoplasia in all the three case were invasive and comprised of pleomorphic, anaplastic with polygonal to very elongated fusiform shapes arranged in a diffuse solid pattern, forming interwoven bundles in some areas. Immunohistochemistry was used to better classify these tumors. The diagnosis of peripheral nerve sheath tumor was confirmed by histological and immunohistochemical findings.