Coronavirus disease 2019 and vaccination in patients with Shwachman-Diamond syndrome

被引:2
|
作者
Galletta, Thomas J. [1 ]
Loveless, Sara K. [2 ]
Malsch, Maggie M. [3 ]
Shimamura, Akiko [4 ,5 ]
Myers, Kasiani C. [2 ,6 ]
机构
[1] Cincinnati Childrens Hosp Med Ctr, Canc & Blood Dis Inst, Cincinnati, OH 45229 USA
[2] Cincinnati Childrens Hosp Med Ctr, Div Bone Marrow Transplantat & Immune Deficiency, Cincinnati, OH 45229 USA
[3] Boston Childrens Hosp, Inst Ctr Clin & Translat Res, Boston, MA USA
[4] Dana Farber Boston Childrens Canc & Blood Disorde, Boston, MA USA
[5] Harvard Med Sch, Dept Pediat, Boston, MA 02115 USA
[6] Univ Cincinnati, Coll Med, Dept Pediat, Cincinnati, OH USA
关键词
Bone marrow failure; COVID-19; general hematology; infections in immunocompromised hosts; infectious disease; vaccines; viral infection;
D O I
10.1002/pbc.29647
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Because they can experience neutropenia due to bone marrow failure, patients with Shwachman-Diamond syndrome (SDS) carry increased risk for serious infections compared with the general population; however, there has been a paucity of data on the incidence and severity of coronavirus disease 2019 (COVID-19) in patients with SDS. We compiled results from a survey distributed to participants in the SDS Registry in May-June 2021. In this report, we describe the characteristics and outcomes of patients with SDS who had COVID-19. Patients reported a short clinical course without significant complications or cytopenias. Additionally, COVID-19 vaccines were well tolerated with minor side effects.
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页数:4
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