Chemoprevention by Triticum Aestivum of Mouse Skin Carcinogenesis Induced by DMBA and Croton Oil - Association with Oxidative Status

被引：0

作者：

Arya, Priyanka ^{[1
]}

Kumar, Madhu ^{[1
]}

机构：

[1] Univ Rajasthan, Dept Zool, Cell & Mol Biol Lab, Ctr Adv Studies, Jaipur 302004, Rajasthan, India

来源：

ASIAN PACIFIC JOURNAL OF CANCER PREVENTION | 2011年 / 12卷 / 01期

关键词：

Chemoprevention; wheat grass leaves extract; papillomas; GSH; SOD; CAT; LPO; INDUCED PAPILLOMAGENESIS; GLUTATHIONE-PEROXIDASE; CANCER; CHLOROPHYLL; PREVENTION; MICRONUTRIENTS; VEGETABLES; STRESS; FRUIT; HEME;

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Chemopreventive action of wheat grass (Triticum astivum) leaf extract in Swiss albino mice was evaluated. Oral administration of wheat grass leaf extract at a dose level of 20 ml/kg body weight per day at pre, peri, and post-initional phases and in combination group, caused significant variation in tumour incidence and tumour yield as compared to the control group. Moreover, the average latent period was significantly increased from 9.87 +/- 0.12 to 13.4 +/- 0.23 weeks in the combination group, together with significant elevation of reduced glutathione (GSH), superoxide dismutase (SOD) catalase (CAT) and reduction in lipid peroxidation (LPO) was observed as compared to the control group.

引用

页码：143 / 148

页数：6

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